Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HMT-3522 S1 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 7911.011 | 0.9416 | 0.9269 | 1.6150 | |
| HMT-3522 S1 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7911.011 | 0.6938 | 0.5948 | 1.6150 | |
| HMT-3522 S1 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7911.011 | 0.1233 | -0.4528 | 1.6150 | |
| HMT-3522 S1 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7911.011 | 0.0315 | -0.7650 | 1.6150 | |
| HMT-3522 S1 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 10124.021 | 1.1668 | 1.1626 | 1.9744 | |
| HMT-3522 S1 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 10124.021 | 0.9537 | 0.9526 | 1.9744 | |
| HMT-3522 S1 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 10124.021 | 1.0889 | 1.0881 | 1.9744 | |
| HMT-3522 S1 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 10124.021 | 1.2047 | 1.1978 | 1.9744 | |
| HMT-3522 S1 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 10124.021 | 1.0183 | 1.0185 | 1.9744 | |
| HMT-3522 S1 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 10124.021 | 0.8416 | 0.8327 | 1.9744 | |
| HMT-3522 S1 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 10124.021 | 0.5303 | 0.4504 | 1.9744 | |
| HMT-3522 S1 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 10124.021 | 0.1052 | -0.3607 | 1.9744 | |
| HMT-3522 S1 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 10124.021 | 0.1239 | -0.3056 | 1.9744 | |
| HMT-3522 T4-2 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 10147.021 | 1.0578 | 1.0521 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 10147.021 | 0.8937 | 0.8997 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 10147.021 | 0.9739 | 0.9760 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 10147.021 | 0.9984 | 0.9985 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 10147.021 | 0.8100 | 0.8162 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 10147.021 | 0.5103 | 0.4701 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 10147.021 | 0.4347 | 0.3661 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 10147.021 | 0.3082 | 0.1673 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 10147.021 | 0.0042 | -0.8372 | 2.1856 | |
| Hs 578T | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7862.011 | 0.9164 | 0.8765 | 1.3695 | |
| Hs 578T | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7862.011 | 1.0023 | 1.0034 | 1.3695 | |
| Hs 578T | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7862.011 | 0.9457 | 0.9200 | 1.3695 |