Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 10419.066 | 1.0260 | 1.0750 | 0.6963 | |
| MDA-MB-134-VI | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 10419.066 | 0.9909 | 0.9738 | 0.6963 | |
| MDA-MB-134-VI | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 10419.066 | 0.9714 | 0.9184 | 0.6963 | |
| MDA-MB-134-VI | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 10419.066 | 0.9819 | 0.9481 | 0.6963 | |
| MDA-MB-134-VI | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 10419.066 | 0.9269 | 0.7935 | 0.6963 | |
| MDA-MB-134-VI | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 10419.066 | 0.8861 | 0.6810 | 0.6963 | |
| MDA-MB-157 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7496.066 | 0.9602 | 0.9313 | 1.1616 | |
| MDA-MB-157 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7496.066 | 1.0478 | 1.0820 | 1.1616 | |
| MDA-MB-157 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7496.066 | 0.9693 | 0.9471 | 1.1616 | |
| MDA-MB-157 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7496.066 | 1.0507 | 1.0869 | 1.1616 | |
| MDA-MB-157 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7496.066 | 1.0347 | 1.0597 | 1.1616 | |
| MDA-MB-157 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7496.066 | 0.9787 | 0.9633 | 1.1616 | |
| MDA-MB-157 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7496.066 | 1.0073 | 1.0126 | 1.1616 | |
| MDA-MB-157 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7496.066 | 0.9427 | 0.9010 | 1.1616 | |
| MDA-MB-157 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7496.066 | 0.3180 | -0.2540 | 1.1616 | |
| MDA-MB-157 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7498.066 | 1.0209 | 1.0389 | 1.0752 | |
| MDA-MB-157 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7498.066 | 0.9809 | 0.9644 | 1.0752 | |
| MDA-MB-157 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7498.066 | 0.9870 | 0.9758 | 1.0752 | |
| MDA-MB-157 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7498.066 | 1.0103 | 1.0191 | 1.0752 | |
| MDA-MB-157 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7498.066 | 1.0307 | 1.0571 | 1.0752 | |
| MDA-MB-157 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7498.066 | 0.9980 | 0.9963 | 1.0752 | |
| MDA-MB-157 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7498.066 | 1.0114 | 1.0212 | 1.0752 | |
| MDA-MB-157 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7498.066 | 1.0000 | 1.0000 | 1.0752 | |
| MDA-MB-157 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7498.066 | 0.5588 | 0.1639 | 1.0752 | |
| MDA-MB-175-VII | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7499.066 | 0.9437 | 0.8588 | 0.7917 |