Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 12070.159 | 0.0247 | -0.9533 | 0.9846 | |
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 12070.159 | 0.0127 | -0.9763 | 0.9846 | |
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 12070.159 | 0.0144 | -0.9730 | 0.9846 | |
| HCC1143 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 12112.159 | 0.9273 | 0.9205 | 1.8609 | |
| HCC1143 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 12112.159 | 0.9773 | 0.9755 | 1.8609 | |
| HCC1143 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 12112.159 | 0.9636 | 0.9605 | 1.8609 | |
| HCC1143 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 12112.159 | 1.0349 | 1.0373 | 1.8609 | |
| HCC1143 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.267 | uM | 12112.159 | 0.9278 | 0.9211 | 1.8609 | |
| HCC1143 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 1.33 | uM | 12112.159 | 0.8065 | 0.7817 | 1.8609 | |
| HCC1143 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 6.67 | uM | 12112.159 | 0.0091 | -0.8402 | 1.8609 | |
| HCC1143 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 33.3 | uM | 12112.159 | 0.0113 | -0.8205 | 1.8609 | |
| HCC1143 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 167 | uM | 12112.159 | 0.0061 | -0.8704 | 1.8609 | |
| HCC1187 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10518.14 | 1.0935 | 1.1540 | 1.2052 | |
| HCC1187 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10518.14 | 1.0105 | 1.0175 | 1.2052 | |
| HCC1187 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10518.14 | 1.0115 | 1.0191 | 1.2052 | |
| HCC1187 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10518.14 | 0.9272 | 0.8784 | 1.2052 | |
| HCC1187 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10518.14 | 1.0619 | 1.1022 | 1.2052 | |
| HCC1187 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10518.14 | 0.9428 | 0.9046 | 1.2052 | |
| HCC1187 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10518.14 | 0.0099 | -0.9565 | 1.2052 | |
| HCC1187 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10518.14 | 0.0061 | -0.9710 | 1.2052 | |
| HCC1187 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 167 | uM | 10518.14 | 0.0043 | -0.9784 | 1.2052 | |
| HCC1187 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10753.152 | 0.9756 | 0.9642 | 1.3690 | |
| HCC1187 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10753.152 | 0.9117 | 0.8694 | 1.3690 | |
| HCC1187 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10753.152 | 0.9282 | 0.8941 | 1.3690 | |
| HCC1187 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10753.152 | 0.9168 | 0.8770 | 1.3690 |