Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0533 | uM | 7472.066 | 1.0772 | 1.0826 | 1.8363 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.267 | uM | 7472.066 | 0.9365 | 0.9298 | 1.8363 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 1.33 | uM | 7472.066 | 1.2432 | 1.2517 | 1.8363 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 6.67 | uM | 7472.066 | 1.3555 | 1.3603 | 1.8363 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 33.3 | uM | 7472.066 | 1.4315 | 1.4315 | 1.8363 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7473.066 | 1.0043 | 1.0037 | 2.3582 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.000427 | uM | 7473.066 | 2.2730 | 1.8330 | 2.3582 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.00213 | uM | 7473.066 | 1.0243 | 1.0205 | 2.3582 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0107 | uM | 7473.066 | 1.1269 | 1.1040 | 2.3582 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0533 | uM | 7473.066 | 1.3153 | 1.2465 | 2.3582 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.267 | uM | 7473.066 | 2.2091 | 1.7990 | 2.3582 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 1.33 | uM | 7473.066 | 1.2341 | 1.1866 | 2.3582 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 6.67 | uM | 7473.066 | 1.5411 | 1.4026 | 2.3582 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 33.3 | uM | 7473.066 | 1.1552 | 1.1261 | 2.3582 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7474.066 | 0.9826 | 0.9874 | 2.7948 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.000427 | uM | 7474.066 | 0.9422 | 0.9578 | 2.7948 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.00213 | uM | 7474.066 | 1.0538 | 1.0379 | 2.7948 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0107 | uM | 7474.066 | 1.0246 | 1.0175 | 2.7948 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0533 | uM | 7474.066 | 1.0460 | 1.0325 | 2.7948 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.267 | uM | 7474.066 | 0.8989 | 0.9252 | 2.7948 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 1.33 | uM | 7474.066 | 0.9451 | 0.9600 | 2.7948 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 6.67 | uM | 7474.066 | 1.0893 | 1.0622 | 2.7948 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 33.3 | uM | 7474.066 | 1.1583 | 1.1080 | 2.7948 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7475.066 | 1.1632 | 1.1122 | 2.7689 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.000427 | uM | 7475.066 | 1.2187 | 1.1481 | 2.7689 |