Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14625.189 | 0.0013 | -0.8240 | 2.7202 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14625.189 | 0.0004 | -0.8859 | 2.7202 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14625.189 | 0.0004 | -0.8859 | 2.7202 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14625.189 | 0.0003 | -0.8973 | 2.7202 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14625.189 | 0.0003 | -0.8973 | 2.7202 | |
| SUM185PE | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12269.145 | 1.4890 | 3.5114 | 0.4894 | |
| SUM185PE | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12269.145 | 1.4890 | 3.5114 | 0.4894 | |
| SUM185PE | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12269.145 | 1.3632 | 2.7666 | 0.4894 | |
| SUM185PE | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12269.145 | 1.3632 | 2.7666 | 0.4894 | |
| SUM185PE | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12269.145 | 1.5487 | 3.8883 | 0.4894 | |
| SUM185PE | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12269.145 | 1.5487 | 3.8883 | 0.4894 | |
| SUM185PE | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12269.145 | 1.3711 | 2.8114 | 0.4894 | |
| SUM185PE | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12269.145 | 1.3711 | 2.8114 | 0.4894 | |
| SUM185PE | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12269.145 | 0.6308 | -0.2200 | 0.4894 | |
| SUM185PE | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12269.145 | 0.6308 | -0.2200 | 0.4894 | |
| SUM185PE | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12269.145 | 0.4359 | -0.6333 | 0.4894 | |
| SUM185PE | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12269.145 | 0.4359 | -0.6333 | 0.4894 | |
| SUM185PE | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12269.145 | 0.2225 | -0.9073 | 0.4894 | |
| SUM185PE | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12269.145 | 0.2225 | -0.9073 | 0.4894 | |
| SUM185PE | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12269.145 | 0.1346 | -0.9668 | 0.4894 | |
| SUM185PE | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12269.145 | 0.1346 | -0.9668 | 0.4894 | |
| SUM185PE | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12269.145 | 0.0652 | -0.9924 | 0.4894 | |
| SUM185PE | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12269.145 | 0.0652 | -0.9924 | 0.4894 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10579.145 | 0.8952 | 0.8027 | 1.0664 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10579.145 | 0.8952 | 0.8027 | 1.0664 |