Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10579.145 | 1.0424 | 1.0795 | 1.0664 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10579.145 | 1.0424 | 1.0795 | 1.0664 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10579.145 | 1.0576 | 1.1079 | 1.0664 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10579.145 | 1.0576 | 1.1079 | 1.0664 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10579.145 | 1.0446 | 1.0835 | 1.0664 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10579.145 | 1.0446 | 1.0835 | 1.0664 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10579.145 | 0.6553 | 0.3455 | 1.0664 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10579.145 | 0.6553 | 0.3455 | 1.0664 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10579.145 | 0.4603 | -0.0338 | 1.0664 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10579.145 | 0.4603 | -0.0338 | 1.0664 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10579.145 | 0.2673 | -0.4195 | 1.0664 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10579.145 | 0.2673 | -0.4195 | 1.0664 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10579.145 | 0.1920 | -0.5744 | 1.0664 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10579.145 | 0.1920 | -0.5744 | 1.0664 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10579.145 | 0.1961 | -0.5659 | 1.0664 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10579.145 | 0.1961 | -0.5659 | 1.0664 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12098.145 | 1.0054 | 1.0110 | 0.9769 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12098.145 | 1.0054 | 1.0110 | 0.9769 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12098.145 | 1.0052 | 1.0106 | 0.9769 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12098.145 | 1.0052 | 1.0106 | 0.9769 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12098.145 | 0.9713 | 0.9413 | 0.9769 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12098.145 | 0.9713 | 0.9413 | 0.9769 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12098.145 | 1.0861 | 1.1764 | 0.9769 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12098.145 | 1.0861 | 1.1764 | 0.9769 | |
| SUM225CWN | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12098.145 | 0.5859 | 0.1570 | 0.9769 |