Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7542.098 | 0.9222 | 0.8795 | 1.3028 | |
| T47D | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.0000427 | uM | 7543.098 | 0.9788 | 0.9707 | 1.4503 | |
| T47D | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7543.098 | 0.9856 | 0.9802 | 1.4503 | |
| T47D | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7543.098 | 1.0447 | 1.0612 | 1.4503 | |
| T47D | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7543.098 | 1.0319 | 1.0438 | 1.4503 | |
| T47D | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7543.098 | 0.9921 | 0.9891 | 1.4503 | |
| T47D | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7543.098 | 0.9414 | 0.9184 | 1.4503 | |
| T47D | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7543.098 | 0.8736 | 0.8221 | 1.4503 | |
| T47D | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7543.098 | 0.8511 | 0.7895 | 1.4503 | |
| T47D | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7543.098 | 0.6745 | 0.5244 | 1.4503 | |
| T47DKBLUC | Unknown | Unknown | Lapatinib | EGFR/HER2 | ErbB | 0.0000427 | uM | 7544.098 | 0.9986 | 0.9977 | 1.2438 | |
| T47DKBLUC | Unknown | Unknown | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7544.098 | 0.8759 | 0.7980 | 1.2438 | |
| T47DKBLUC | Unknown | Unknown | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7544.098 | 1.0047 | 1.0076 | 1.2438 | |
| T47DKBLUC | Unknown | Unknown | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7544.098 | 0.9593 | 0.9342 | 1.2438 | |
| T47DKBLUC | Unknown | Unknown | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7544.098 | 0.9814 | 0.9700 | 1.2438 | |
| T47DKBLUC | Unknown | Unknown | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7544.098 | 0.9354 | 0.8954 | 1.2438 | |
| T47DKBLUC | Unknown | Unknown | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7544.098 | 0.9790 | 0.9662 | 1.2438 | |
| T47DKBLUC | Unknown | Unknown | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7544.098 | 1.0109 | 1.0176 | 1.2438 | |
| T47DKBLUC | Unknown | Unknown | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7544.098 | 0.9743 | 0.9586 | 1.2438 | |
| T47DKBLUC | Unknown | Unknown | Lapatinib | EGFR/HER2 | ErbB | 0.0000427 | uM | 7545.098 | 0.9890 | 0.9809 | 1.1555 | |
| T47DKBLUC | Unknown | Unknown | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7545.098 | 0.9382 | 0.8925 | 1.1555 | |
| T47DKBLUC | Unknown | Unknown | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7545.098 | 0.9187 | 0.8586 | 1.1555 | |
| T47DKBLUC | Unknown | Unknown | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7545.098 | 0.9230 | 0.8660 | 1.1555 | |
| T47DKBLUC | Unknown | Unknown | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7545.098 | 0.9889 | 0.9807 | 1.1555 | |
| T47DKBLUC | Unknown | Unknown | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7545.098 | 0.9536 | 0.9194 | 1.1555 |