Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7539.098 | 0.8694 | 0.8349 | 1.6240 | |
| SUM52PE | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7539.098 | 0.8988 | 0.8729 | 1.6240 | |
| SUM52PE | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7539.098 | 0.9337 | 0.9173 | 1.6240 | |
| SUM52PE | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7539.098 | 0.9108 | 0.8882 | 1.6240 | |
| SUM52PE | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7539.098 | 0.8356 | 0.7906 | 1.6240 | |
| SUM52PE | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7539.098 | 0.9449 | 0.9314 | 1.6240 | |
| SUM52PE | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7539.098 | 0.8837 | 0.8534 | 1.6240 | |
| SUM52PE | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7539.098 | 0.8819 | 0.8510 | 1.6240 | |
| SUM52PE | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.0000427 | uM | 7541.098 | 0.9061 | 0.8824 | 1.6271 | |
| SUM52PE | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7541.098 | 0.8955 | 0.8689 | 1.6271 | |
| SUM52PE | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7541.098 | 0.9226 | 0.9034 | 1.6271 | |
| SUM52PE | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7541.098 | 0.8417 | 0.7990 | 1.6271 | |
| SUM52PE | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7541.098 | 0.9108 | 0.8884 | 1.6271 | |
| SUM52PE | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7541.098 | 0.9095 | 0.8867 | 1.6271 | |
| SUM52PE | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7541.098 | 0.8851 | 0.8554 | 1.6271 | |
| SUM52PE | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7541.098 | 0.9154 | 0.8942 | 1.6271 | |
| SUM52PE | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7541.098 | 0.8419 | 0.7993 | 1.6271 | |
| T47D | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.0000427 | uM | 7542.098 | 1.0219 | 1.0336 | 1.3028 | |
| T47D | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7542.098 | 0.9319 | 0.8947 | 1.3028 | |
| T47D | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7542.098 | 0.9752 | 0.9618 | 1.3028 | |
| T47D | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7542.098 | 0.9788 | 0.9674 | 1.3028 | |
| T47D | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7542.098 | 1.0019 | 1.0029 | 1.3028 | |
| T47D | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7542.098 | 0.9614 | 0.9405 | 1.3028 | |
| T47D | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7542.098 | 0.9196 | 0.8754 | 1.3028 | |
| T47D | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7542.098 | 0.9584 | 0.9358 | 1.3028 |