Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-549 | TNBC | Basal B | Ibandronate | FDPS | 12 | uM | 12305.143 | 0.7550 | 0.8159 | 2.9115 | ||
| BT-549 | TNBC | Basal B | Ibandronate | FDPS | 60 | uM | 12305.143 | 0.3872 | 0.4438 | 2.9115 | ||
| BT-549 | TNBC | Basal B | Ibandronate | FDPS | 300 | uM | 12305.143 | 0.1860 | 0.1223 | 2.9115 | ||
| BT-549 | TNBC | Basal B | Ibandronate | FDPS | 1500 | uM | 12305.143 | 0.0912 | -0.1213 | 2.9115 | ||
| CAMA-1 | HR+ | Luminal | Ibandronate | FDPS | 0.00384 | uM | 10755.143 | 0.9581 | 0.9074 | 0.9034 | ||
| CAMA-1 | HR+ | Luminal | Ibandronate | FDPS | 0.0192 | uM | 10755.143 | 0.8780 | 0.7318 | 0.9034 | ||
| CAMA-1 | HR+ | Luminal | Ibandronate | FDPS | 0.096 | uM | 10755.143 | 0.9921 | 0.9825 | 0.9034 | ||
| CAMA-1 | HR+ | Luminal | Ibandronate | FDPS | 0.48 | uM | 10755.143 | 0.9841 | 0.9649 | 0.9034 | ||
| CAMA-1 | HR+ | Luminal | Ibandronate | FDPS | 2.4 | uM | 10755.143 | 0.9399 | 0.8675 | 0.9034 | ||
| CAMA-1 | HR+ | Luminal | Ibandronate | FDPS | 12 | uM | 10755.143 | 0.9760 | 0.9470 | 0.9034 | ||
| CAMA-1 | HR+ | Luminal | Ibandronate | FDPS | 60 | uM | 10755.143 | 0.8675 | 0.7089 | 0.9034 | ||
| CAMA-1 | HR+ | Luminal | Ibandronate | FDPS | 300 | uM | 10755.143 | 0.4092 | -0.2563 | 0.9034 | ||
| CAMA-1 | HR+ | Luminal | Ibandronate | FDPS | 1500 | uM | 10755.143 | 0.1292 | -0.7925 | 0.9034 | ||
| CAMA-1 | HR+ | Luminal | Ibandronate | FDPS | 0.00384 | uM | 12070.143 | 1.0219 | 1.0458 | 0.9561 | ||
| CAMA-1 | HR+ | Luminal | Ibandronate | FDPS | 0.0192 | uM | 12070.143 | 0.9957 | 0.9911 | 0.9561 | ||
| CAMA-1 | HR+ | Luminal | Ibandronate | FDPS | 0.096 | uM | 12070.143 | 1.0168 | 1.0352 | 0.9561 | ||
| CAMA-1 | HR+ | Luminal | Ibandronate | FDPS | 0.48 | uM | 12070.143 | 1.0434 | 1.0908 | 0.9561 | ||
| CAMA-1 | HR+ | Luminal | Ibandronate | FDPS | 2.4 | uM | 12070.143 | 1.0326 | 1.0683 | 0.9561 | ||
| CAMA-1 | HR+ | Luminal | Ibandronate | FDPS | 12 | uM | 12070.143 | 1.0299 | 1.0625 | 0.9561 | ||
| CAMA-1 | HR+ | Luminal | Ibandronate | FDPS | 60 | uM | 12070.143 | 1.0170 | 1.0357 | 0.9561 | ||
| CAMA-1 | HR+ | Luminal | Ibandronate | FDPS | 300 | uM | 12070.143 | 0.3910 | -0.2511 | 0.9561 | ||
| CAMA-1 | HR+ | Luminal | Ibandronate | FDPS | 1500 | uM | 12070.143 | 0.1207 | -0.7810 | 0.9561 | ||
| HCC1143 | TNBC | Basal A | Ibandronate | FDPS | 0.00384 | uM | 12112.143 | 0.9958 | 0.9950 | 1.6893 | ||
| HCC1143 | TNBC | Basal A | Ibandronate | FDPS | 0.0192 | uM | 12112.143 | 1.0112 | 1.0133 | 1.6893 | ||
| HCC1143 | TNBC | Basal A | Ibandronate | FDPS | 0.096 | uM | 12112.143 | 1.0098 | 1.0115 | 1.6893 |