Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 300 | uM | 12291.143 | 0.5524 | -0.3042 | 0.5621 | ||
| BT-474 | HER2amp | Luminal | Ibandronate | FDPS | 1500 | uM | 12291.143 | 0.5951 | -0.2057 | 0.5621 | ||
| BT-483 | HR+ | Luminal | Ibandronate | FDPS | 0.00384 | uM | 10696.143 | 1.0190 | 1.0738 | 0.5188 | ||
| BT-483 | HR+ | Luminal | Ibandronate | FDPS | 0.0192 | uM | 10696.143 | 0.9717 | 0.8922 | 0.5188 | ||
| BT-483 | HR+ | Luminal | Ibandronate | FDPS | 0.096 | uM | 10696.143 | 1.0173 | 1.0671 | 0.5188 | ||
| BT-483 | HR+ | Luminal | Ibandronate | FDPS | 0.48 | uM | 10696.143 | 1.0188 | 1.0731 | 0.5188 | ||
| BT-483 | HR+ | Luminal | Ibandronate | FDPS | 2.4 | uM | 10696.143 | 0.9730 | 0.8971 | 0.5188 | ||
| BT-483 | HR+ | Luminal | Ibandronate | FDPS | 12 | uM | 10696.143 | 0.9774 | 0.9139 | 0.5188 | ||
| BT-483 | HR+ | Luminal | Ibandronate | FDPS | 60 | uM | 10696.143 | 0.8584 | 0.4901 | 0.5188 | ||
| BT-483 | HR+ | Luminal | Ibandronate | FDPS | 300 | uM | 10696.143 | 0.5804 | -0.2993 | 0.5188 | ||
| BT-483 | HR+ | Luminal | Ibandronate | FDPS | 1500 | uM | 10696.143 | 0.4909 | -0.4926 | 0.5188 | ||
| BT-483 | HR+ | Luminal | Ibandronate | FDPS | 0.00384 | uM | 11855.143 | 0.9868 | 0.9509 | 0.5372 | ||
| BT-483 | HR+ | Luminal | Ibandronate | FDPS | 0.0192 | uM | 11855.143 | 0.9245 | 0.7281 | 0.5372 | ||
| BT-483 | HR+ | Luminal | Ibandronate | FDPS | 0.096 | uM | 11855.143 | 0.9945 | 0.9795 | 0.5372 | ||
| BT-483 | HR+ | Luminal | Ibandronate | FDPS | 0.48 | uM | 11855.143 | 0.9852 | 0.9451 | 0.5372 | ||
| BT-483 | HR+ | Luminal | Ibandronate | FDPS | 2.4 | uM | 11855.143 | 0.9580 | 0.8464 | 0.5372 | ||
| BT-483 | HR+ | Luminal | Ibandronate | FDPS | 12 | uM | 11855.143 | 0.9757 | 0.9103 | 0.5372 | ||
| BT-483 | HR+ | Luminal | Ibandronate | FDPS | 60 | uM | 11855.143 | 0.8041 | 0.3329 | 0.5372 | ||
| BT-483 | HR+ | Luminal | Ibandronate | FDPS | 300 | uM | 11855.143 | 0.6047 | -0.2160 | 0.5372 | ||
| BT-483 | HR+ | Luminal | Ibandronate | FDPS | 1500 | uM | 11855.143 | 0.5035 | -0.4425 | 0.5372 | ||
| BT-549 | TNBC | Basal B | Ibandronate | FDPS | 0.00384 | uM | 12305.143 | 1.0361 | 1.0245 | 2.9115 | ||
| BT-549 | TNBC | Basal B | Ibandronate | FDPS | 0.0192 | uM | 12305.143 | 1.0240 | 1.0164 | 2.9115 | ||
| BT-549 | TNBC | Basal B | Ibandronate | FDPS | 0.096 | uM | 12305.143 | 0.9878 | 0.9916 | 2.9115 | ||
| BT-549 | TNBC | Basal B | Ibandronate | FDPS | 0.48 | uM | 12305.143 | 0.9634 | 0.9745 | 2.9115 | ||
| BT-549 | TNBC | Basal B | Ibandronate | FDPS | 2.4 | uM | 12305.143 | 0.9051 | 0.9327 | 2.9115 |