Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | GW843682X | PLK | PLK | 0.000427 | uM | 10578.139 | 0.9594 | 0.9502 | 1.6434 | |
| HCC38 | TNBC | Basal B | GW843682X | PLK | PLK | 0.00213 | uM | 10578.139 | 1.0070 | 1.0085 | 1.6434 | |
| HCC38 | TNBC | Basal B | GW843682X | PLK | PLK | 0.0107 | uM | 10578.139 | 1.0428 | 1.0517 | 1.6434 | |
| HCC38 | TNBC | Basal B | GW843682X | PLK | PLK | 0.0533 | uM | 10578.139 | 1.0747 | 1.0897 | 1.6434 | |
| HCC38 | TNBC | Basal B | GW843682X | PLK | PLK | 0.267 | uM | 10578.139 | 0.9607 | 0.9518 | 1.6434 | |
| HCC38 | TNBC | Basal B | GW843682X | PLK | PLK | 1.33 | uM | 10578.139 | 1.0685 | 1.0823 | 1.6434 | |
| HCC38 | TNBC | Basal B | GW843682X | PLK | PLK | 6.67 | uM | 10578.139 | 0.9990 | 0.9988 | 1.6434 | |
| HCC38 | TNBC | Basal B | GW843682X | PLK | PLK | 33.3 | uM | 10578.139 | 1.0501 | 1.0603 | 1.6434 | |
| MDA-MB-134-VI | HR+ | Luminal | GW843682X | PLK | PLK | 0.0000853 | uM | 10519.139 | 1.0225 | 1.0442 | 1.0177 | |
| MDA-MB-134-VI | HR+ | Luminal | GW843682X | PLK | PLK | 0.000427 | uM | 10519.139 | 0.9315 | 0.8654 | 1.0177 | |
| MDA-MB-134-VI | HR+ | Luminal | GW843682X | PLK | PLK | 0.00213 | uM | 10519.139 | 0.9692 | 0.9395 | 1.0177 | |
| MDA-MB-134-VI | HR+ | Luminal | GW843682X | PLK | PLK | 0.0107 | uM | 10519.139 | 1.0469 | 1.0920 | 1.0177 | |
| MDA-MB-134-VI | HR+ | Luminal | GW843682X | PLK | PLK | 0.0533 | uM | 10519.139 | 1.0503 | 1.0989 | 1.0177 | |
| MDA-MB-134-VI | HR+ | Luminal | GW843682X | PLK | PLK | 0.267 | uM | 10519.139 | 0.9714 | 0.9439 | 1.0177 | |
| MDA-MB-134-VI | HR+ | Luminal | GW843682X | PLK | PLK | 1.33 | uM | 10519.139 | 1.0134 | 1.0263 | 1.0177 | |
| MDA-MB-134-VI | HR+ | Luminal | GW843682X | PLK | PLK | 6.67 | uM | 10519.139 | 0.8279 | 0.6612 | 1.0177 | |
| MDA-MB-134-VI | HR+ | Luminal | GW843682X | PLK | PLK | 33.3 | uM | 10519.139 | 0.5628 | 0.1368 | 1.0177 | |
| MDA-MB-175-VII | HR+ | Luminal | GW843682X | PLK | PLK | 0.0000853 | uM | 10642.139 | 0.9903 | 0.9724 | 0.7017 | |
| MDA-MB-175-VII | HR+ | Luminal | GW843682X | PLK | PLK | 0.000427 | uM | 10642.139 | 0.9788 | 0.9400 | 0.7017 | |
| MDA-MB-175-VII | HR+ | Luminal | GW843682X | PLK | PLK | 0.00213 | uM | 10642.139 | 0.9820 | 0.9489 | 0.7017 | |
| MDA-MB-175-VII | HR+ | Luminal | GW843682X | PLK | PLK | 0.0107 | uM | 10642.139 | 0.9603 | 0.8877 | 0.7017 | |
| MDA-MB-175-VII | HR+ | Luminal | GW843682X | PLK | PLK | 0.0533 | uM | 10642.139 | 0.9576 | 0.8803 | 0.7017 | |
| MDA-MB-175-VII | HR+ | Luminal | GW843682X | PLK | PLK | 0.267 | uM | 10642.139 | 1.0407 | 1.1169 | 0.7017 | |
| MDA-MB-175-VII | HR+ | Luminal | GW843682X | PLK | PLK | 1.33 | uM | 10642.139 | 1.0184 | 1.0528 | 0.7017 | |
| MDA-MB-175-VII | HR+ | Luminal | GW843682X | PLK | PLK | 6.67 | uM | 10642.139 | 0.9595 | 0.8856 | 0.7017 |