Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | GW843682X | PLK | PLK | 0.0107 | uM | 10473.139 | 0.9836 | 0.9727 | 1.2054 | |
| CAMA-1 | HR+ | Luminal | GW843682X | PLK | PLK | 0.0533 | uM | 10473.139 | 1.0150 | 1.0249 | 1.2054 | |
| CAMA-1 | HR+ | Luminal | GW843682X | PLK | PLK | 0.267 | uM | 10473.139 | 0.9724 | 0.9540 | 1.2054 | |
| CAMA-1 | HR+ | Luminal | GW843682X | PLK | PLK | 1.33 | uM | 10473.139 | 1.0121 | 1.0201 | 1.2054 | |
| CAMA-1 | HR+ | Luminal | GW843682X | PLK | PLK | 6.67 | uM | 10473.139 | 0.9857 | 0.9763 | 1.2054 | |
| CAMA-1 | HR+ | Luminal | GW843682X | PLK | PLK | 33.3 | uM | 10473.139 | 0.8927 | 0.8203 | 1.2054 | |
| HCC1187 | TNBC | Basal A | GW843682X | PLK | PLK | 0.0000853 | uM | 10518.139 | 1.0276 | 1.0446 | 1.2366 | |
| HCC1187 | TNBC | Basal A | GW843682X | PLK | PLK | 0.000427 | uM | 10518.139 | 0.9696 | 0.9507 | 1.2366 | |
| HCC1187 | TNBC | Basal A | GW843682X | PLK | PLK | 0.00213 | uM | 10518.139 | 0.9522 | 0.9223 | 1.2366 | |
| HCC1187 | TNBC | Basal A | GW843682X | PLK | PLK | 0.0107 | uM | 10518.139 | 0.9764 | 0.9618 | 1.2366 | |
| HCC1187 | TNBC | Basal A | GW843682X | PLK | PLK | 0.0533 | uM | 10518.139 | 1.0037 | 1.0060 | 1.2366 | |
| HCC1187 | TNBC | Basal A | GW843682X | PLK | PLK | 0.267 | uM | 10518.139 | 0.9110 | 0.8548 | 1.2366 | |
| HCC1187 | TNBC | Basal A | GW843682X | PLK | PLK | 1.33 | uM | 10518.139 | 0.8706 | 0.7880 | 1.2366 | |
| HCC1187 | TNBC | Basal A | GW843682X | PLK | PLK | 6.67 | uM | 10518.139 | 0.7457 | 0.5775 | 1.2366 | |
| HCC1187 | TNBC | Basal A | GW843682X | PLK | PLK | 33.3 | uM | 10518.139 | 0.5401 | 0.2153 | 1.2366 | |
| HCC3153 | TNBC | Basal A | GW843682X | PLK | PLK | 0.0000853 | uM | 10577.139 | 1.0645 | 1.1402 | 0.9234 | |
| HCC3153 | TNBC | Basal A | GW843682X | PLK | PLK | 0.000427 | uM | 10577.139 | 0.9832 | 0.9636 | 0.9234 | |
| HCC3153 | TNBC | Basal A | GW843682X | PLK | PLK | 0.00213 | uM | 10577.139 | 0.9789 | 0.9542 | 0.9234 | |
| HCC3153 | TNBC | Basal A | GW843682X | PLK | PLK | 0.0107 | uM | 10577.139 | 1.0878 | 1.1908 | 0.9234 | |
| HCC3153 | TNBC | Basal A | GW843682X | PLK | PLK | 0.0533 | uM | 10577.139 | 1.1159 | 1.2522 | 0.9234 | |
| HCC3153 | TNBC | Basal A | GW843682X | PLK | PLK | 0.267 | uM | 10577.139 | 1.0196 | 1.0424 | 0.9234 | |
| HCC3153 | TNBC | Basal A | GW843682X | PLK | PLK | 1.33 | uM | 10577.139 | 1.0586 | 1.1271 | 0.9234 | |
| HCC3153 | TNBC | Basal A | GW843682X | PLK | PLK | 6.67 | uM | 10577.139 | 1.0620 | 1.1346 | 0.9234 | |
| HCC3153 | TNBC | Basal A | GW843682X | PLK | PLK | 33.3 | uM | 10577.139 | 1.0261 | 1.0566 | 0.9234 | |
| HCC38 | TNBC | Basal B | GW843682X | PLK | PLK | 0.0000853 | uM | 10578.139 | 1.0741 | 1.0890 | 1.6434 |