Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-468 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 7906.001 | 0.8999 | 0.6613 | 0.5685 | |
| MDA-MB-468 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 7906.001 | 0.6177 | -0.1430 | 0.5685 | |
| MDA-MB-468 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 7906.001 | 0.9530 | 0.8377 | 0.5685 | |
| MDA-MB-468 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 7906.001 | 0.9240 | 0.7403 | 0.5685 | |
| MDA-MB-468 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 7906.001 | 0.3096 | -0.7457 | 0.5685 | |
| MDA-MB-468 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.267 | uM | 7906.001 | 0.0742 | -0.9794 | 0.5685 | |
| MDA-MB-468 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 1.33 | uM | 7906.001 | 0.0965 | -0.9673 | 0.5685 | |
| MDA-MB-468 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 6.67 | uM | 7906.001 | 0.2735 | -0.7956 | 0.5685 | |
| MDA-MB-468 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 33.3 | uM | 7906.001 | 0.0929 | -0.9694 | 0.5685 | |
| MDA-MB-468 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 7907.001 | 1.1422 | 1.2102 | 1.3308 | |
| MDA-MB-468 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 7907.001 | 0.8976 | 0.8440 | 1.3308 | |
| MDA-MB-468 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 7907.001 | 1.1814 | 1.2669 | 1.3308 | |
| MDA-MB-468 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 7907.001 | 0.7812 | 0.6613 | 1.3308 | |
| MDA-MB-468 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 7907.001 | 0.2155 | -0.3687 | 1.3308 | |
| MDA-MB-468 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.267 | uM | 7907.001 | 0.0791 | -0.7027 | 1.3308 | |
| MDA-MB-468 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 1.33 | uM | 7907.001 | 0.1144 | -0.6078 | 1.3308 | |
| MDA-MB-468 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 6.67 | uM | 7907.001 | 0.1590 | -0.4977 | 1.3308 | |
| MDA-MB-468 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 33.3 | uM | 7907.001 | 0.0814 | -0.6962 | 1.3308 | |
| MDA-MB-468 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 7909.001 | 1.0572 | 1.0711 | 1.5909 | |
| MDA-MB-468 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 7909.001 | 0.9477 | 0.9336 | 1.5909 | |
| MDA-MB-468 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 7909.001 | 1.1706 | 1.2081 | 1.5909 | |
| MDA-MB-468 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 7909.001 | 0.7400 | 0.6551 | 1.5909 | |
| MDA-MB-468 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 7909.001 | 0.4898 | 0.2769 | 1.5909 | |
| MDA-MB-468 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 0.267 | uM | 7909.001 | 0.1324 | -0.4388 | 1.5909 | |
| MDA-MB-468 | TNBC | Basal A | GSK923295 | CENPE | Kinesin | 1.33 | uM | 7909.001 | 0.2291 | -0.2079 | 1.5909 |