Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | IKK16 | IKK | NFKB | 13.3 | uM | 10520.1 | 0.0009 | -0.7137 | 3.6151 | |
| SUM159PT | TNBC | Basal B | IKK16 | IKK | NFKB | 66.7 | uM | 10520.1 | 0.0009 | -0.7137 | 3.6151 | |
| SUM225CWN | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.000171 | uM | 10579.1 | 0.9689 | 0.9357 | 0.9677 | |
| SUM225CWN | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.000853 | uM | 10579.1 | 1.0059 | 1.0121 | 0.9677 | |
| SUM225CWN | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.00427 | uM | 10579.1 | 0.9393 | 0.8747 | 0.9677 | |
| SUM225CWN | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.0213 | uM | 10579.1 | 0.9400 | 0.8761 | 0.9677 | |
| SUM225CWN | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.107 | uM | 10579.1 | 1.0813 | 1.1682 | 0.9677 | |
| SUM225CWN | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.533 | uM | 10579.1 | 0.9398 | 0.8758 | 0.9677 | |
| SUM225CWN | HER2amp | Basal A | IKK16 | IKK | NFKB | 2.67 | uM | 10579.1 | 0.8090 | 0.6065 | 0.9677 | |
| SUM225CWN | HER2amp | Basal A | IKK16 | IKK | NFKB | 13.3 | uM | 10579.1 | 0.0172 | -0.9700 | 0.9677 | |
| SUM225CWN | HER2amp | Basal A | IKK16 | IKK | NFKB | 66.7 | uM | 10579.1 | 0.0088 | -0.9851 | 0.9677 | |
| SUM229PE | TNBC | - | IKK16 | IKK | NFKB | 0.000171 | uM | 7535.1 | 1.0235 | 1.0538 | 0.8740 | |
| SUM229PE | TNBC | - | IKK16 | IKK | NFKB | 0.000853 | uM | 7535.1 | 0.9289 | 0.8381 | 0.8740 | |
| SUM229PE | TNBC | - | IKK16 | IKK | NFKB | 0.00427 | uM | 7535.1 | 0.9582 | 0.9047 | 0.8740 | |
| SUM229PE | TNBC | - | IKK16 | IKK | NFKB | 0.0213 | uM | 7535.1 | 0.9951 | 0.9888 | 0.8740 | |
| SUM229PE | TNBC | - | IKK16 | IKK | NFKB | 0.107 | uM | 7535.1 | 0.9841 | 0.9637 | 0.8740 | |
| SUM229PE | TNBC | - | IKK16 | IKK | NFKB | 0.533 | uM | 7535.1 | 0.8891 | 0.7483 | 0.8740 | |
| SUM229PE | TNBC | - | IKK16 | IKK | NFKB | 2.67 | uM | 7535.1 | 0.3851 | -0.3287 | 0.8740 | |
| SUM229PE | TNBC | - | IKK16 | IKK | NFKB | 13.3 | uM | 7535.1 | 0.0089 | -0.9910 | 0.8740 | |
| SUM229PE | TNBC | - | IKK16 | IKK | NFKB | 66.7 | uM | 7535.1 | 0.0080 | -0.9920 | 0.8740 | |
| SUM52PE | HR+ | Luminal | IKK16 | IKK | NFKB | 0.000171 | uM | 7539.093 | 0.9162 | 0.8930 | 1.5919 | |
| SUM52PE | HR+ | Luminal | IKK16 | IKK | NFKB | 0.000853 | uM | 7539.093 | 0.8711 | 0.8339 | 1.5919 | |
| SUM52PE | HR+ | Luminal | IKK16 | IKK | NFKB | 0.00427 | uM | 7539.093 | 0.8373 | 0.7889 | 1.5919 | |
| SUM52PE | HR+ | Luminal | IKK16 | IKK | NFKB | 0.0213 | uM | 7539.093 | 0.9068 | 0.8807 | 1.5919 | |
| SUM52PE | HR+ | Luminal | IKK16 | IKK | NFKB | 0.107 | uM | 7539.093 | 0.9789 | 0.9734 | 1.5919 |