Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM102PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 9777.001 | 0.9441 | 0.8469 | 0.7223 | |
| SUM102PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.000427 | uM | 9777.001 | 0.9781 | 0.9396 | 0.7223 | |
| SUM102PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.00213 | uM | 9777.001 | 1.2024 | 1.5814 | 0.7223 | |
| SUM102PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0107 | uM | 9777.001 | 0.9562 | 0.8797 | 0.7223 | |
| SUM102PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0533 | uM | 9777.001 | 1.0680 | 1.1906 | 0.7223 | |
| SUM102PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.267 | uM | 9777.001 | 1.0166 | 1.0462 | 0.7223 | |
| SUM102PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 1.33 | uM | 9777.001 | 0.9766 | 0.9355 | 0.7223 | |
| SUM102PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 6.67 | uM | 9777.001 | 0.6337 | 0.0635 | 0.7223 | |
| SUM102PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 33.3 | uM | 9777.001 | 0.0023 | -0.9996 | 0.7223 | |
| SUM1315MO2 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 9797.001 | 0.9772 | 0.9248 | 0.6012 | |
| SUM1315MO2 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.000427 | uM | 9797.001 | 1.0171 | 1.0571 | 0.6012 | |
| SUM1315MO2 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.00213 | uM | 9797.001 | 0.9192 | 0.7383 | 0.6012 | |
| SUM1315MO2 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0107 | uM | 9797.001 | 1.0019 | 1.0063 | 0.6012 | |
| SUM1315MO2 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0533 | uM | 9797.001 | 0.3222 | -0.6960 | 0.6012 | |
| SUM1315MO2 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.267 | uM | 9797.001 | 0.3003 | -0.7296 | 0.6012 | |
| SUM1315MO2 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 1.33 | uM | 9797.001 | 0.3252 | -0.6913 | 0.6012 | |
| SUM1315MO2 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 6.67 | uM | 9797.001 | 0.2411 | -0.8124 | 0.6012 | |
| SUM1315MO2 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 33.3 | uM | 9797.001 | 0.2322 | -0.8237 | 0.6012 | |
| SUM1315MO2 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 10139.001 | 0.9836 | 0.9555 | 0.7336 | |
| SUM1315MO2 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.000427 | uM | 10139.001 | 1.0119 | 1.0326 | 0.7336 | |
| SUM1315MO2 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.00213 | uM | 10139.001 | 0.9900 | 0.9728 | 0.7336 | |
| SUM1315MO2 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0107 | uM | 10139.001 | 0.9597 | 0.8909 | 0.7336 | |
| SUM1315MO2 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0533 | uM | 10139.001 | 0.4552 | -0.3160 | 0.7336 | |
| SUM1315MO2 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.267 | uM | 10139.001 | 0.3764 | -0.4721 | 0.7336 | |
| SUM1315MO2 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 1.33 | uM | 10139.001 | 0.3610 | -0.5013 | 0.7336 |