Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7553.091 | 0.8478 | 0.6880 | 0.9738 | |
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7553.091 | 0.0210 | -0.9622 | 0.9738 | |
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 7553.091 | 0.0112 | -0.9802 | 0.9738 | |
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7553.098 | 0.9613 | 0.9369 | 1.2325 | |
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7553.098 | 0.9380 | 0.8989 | 1.2325 | |
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7553.098 | 0.9332 | 0.8909 | 1.2325 | |
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7553.098 | 0.9190 | 0.8675 | 1.2325 | |
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7553.098 | 0.9310 | 0.8873 | 1.2325 | |
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7553.098 | 0.8652 | 0.7784 | 1.2325 | |
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7553.098 | 0.8258 | 0.7123 | 1.2325 | |
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7553.098 | 0.5067 | 0.1520 | 1.2325 | |
| ZR-75-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7553.098 | 0.5525 | 0.2359 | 1.2325 | |
| ZR75B | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7555.091 | 1.0737 | 1.0907 | 1.6040 | |
| ZR75B | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7555.091 | 1.0180 | 1.0224 | 1.6040 | |
| ZR75B | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7555.091 | 1.0302 | 1.0374 | 1.6040 | |
| ZR75B | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7555.091 | 1.0612 | 1.0755 | 1.6040 | |
| ZR75B | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7555.091 | 1.0401 | 1.0497 | 1.6040 | |
| ZR75B | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7555.091 | 0.8907 | 0.8608 | 1.6040 | |
| ZR75B | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7555.091 | 0.8902 | 0.8601 | 1.6040 | |
| ZR75B | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7555.091 | 0.0270 | -0.7894 | 1.6040 | |
| ZR75B | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 7555.091 | 0.0271 | -0.7891 | 1.6040 | |
| ZR75B | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7555.098 | 1.0240 | 1.0290 | 1.6495 | |
| ZR75B | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7555.098 | 1.0231 | 1.0278 | 1.6495 | |
| ZR75B | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7555.098 | 0.9806 | 0.9764 | 1.6495 | |
| ZR75B | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7555.098 | 0.9806 | 0.9763 | 1.6495 |