Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7528.098 | 1.0106 | 1.0218 | 0.9717 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7528.098 | 1.0150 | 1.0309 | 0.9717 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7528.098 | 0.9414 | 0.8796 | 0.9717 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7528.098 | 0.8846 | 0.7629 | 0.9717 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7528.098 | 0.8512 | 0.6945 | 0.9717 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7528.098 | 0.8365 | 0.6644 | 0.9717 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7528.098 | 0.8178 | 0.6261 | 0.9717 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7529.09 | 0.9764 | 0.8976 | 0.4538 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7529.09 | 0.9441 | 0.7617 | 0.4538 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7529.09 | 0.9654 | 0.8506 | 0.4538 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7529.09 | 0.9816 | 0.9200 | 0.4538 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7529.09 | 0.9000 | 0.5856 | 0.4538 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7529.09 | 0.4944 | -0.5764 | 0.4538 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7529.09 | 0.8070 | 0.2469 | 0.4538 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7529.09 | 0.7930 | 0.1997 | 0.4538 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 133 | uM | 7529.09 | 0.9104 | 0.6262 | 0.4538 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000307 | uM | 9044.071 | 1.0078 | 1.0247 | 0.6310 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00154 | uM | 9044.071 | 1.0528 | 1.1700 | 0.6310 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00768 | uM | 9044.071 | 1.0448 | 1.1439 | 0.6310 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0384 | uM | 9044.071 | 1.0276 | 1.0883 | 0.6310 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.192 | uM | 9044.071 | 0.9411 | 0.8165 | 0.6310 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.96 | uM | 9044.071 | 0.8325 | 0.4958 | 0.6310 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 4.8 | uM | 9044.071 | 0.8826 | 0.6407 | 0.6310 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 24 | uM | 9044.071 | 0.0201 | -0.9959 | 0.6310 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 120 | uM | 9044.071 | 0.0104 | -0.9986 | 0.6310 |