Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 5894.098 | 1.0678 | 1.0810 | 1.6523 | |
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 5894.098 | 1.0081 | 1.0098 | 1.6523 | |
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 5894.098 | 1.0593 | 1.0710 | 1.6523 | |
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 5894.098 | 1.0040 | 1.0049 | 1.6523 | |
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 5894.098 | 0.9480 | 0.9364 | 1.6523 | |
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 5894.098 | 0.5036 | 0.3205 | 1.6523 | |
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 5894.098 | 0.3535 | 0.0658 | 1.6523 | |
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 5894.098 | 0.3358 | 0.0333 | 1.6523 | |
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 5894.098 | 0.3494 | 0.0584 | 1.6523 | |
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 5895.091 | 1.1229 | 1.2077 | 1.1729 | |
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 5895.091 | 1.1001 | 1.1695 | 1.1729 | |
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 5895.091 | 1.0466 | 1.0792 | 1.1729 | |
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 5895.091 | 1.1019 | 1.1725 | 1.1729 | |
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 5895.091 | 0.8663 | 0.7696 | 1.1729 | |
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 5895.091 | 0.4017 | -0.0809 | 1.1729 | |
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 5895.091 | 0.3918 | -0.1004 | 1.1729 | |
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 5895.091 | 0.1958 | -0.5020 | 1.1729 | |
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 133 | uM | 5895.091 | 0.1501 | -0.6029 | 1.1729 | |
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 5895.098 | 1.0933 | 1.1312 | 1.4041 | |
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 5895.098 | 1.0008 | 1.0011 | 1.4041 | |
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 5895.098 | 1.0581 | 1.0821 | 1.4041 | |
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 5895.098 | 1.0387 | 1.0548 | 1.4041 | |
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 5895.098 | 0.9310 | 0.9007 | 1.4041 | |
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 5895.098 | 0.6126 | 0.4107 | 1.4041 | |
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 5895.098 | 0.4445 | 0.1225 | 1.4041 |