Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 1.33 | uM | 10267.001 | 1.1079 | 1.5909 | 0.3957 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 6.67 | uM | 10267.001 | 1.0288 | 1.1487 | 0.3957 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 33.3 | uM | 10267.001 | 0.7413 | -0.0613 | 0.3957 | |
| UACC-893 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0000853 | uM | 9045.001 | 1.2327 | 1.4803 | 0.9719 | |
| UACC-893 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.000427 | uM | 9045.001 | 0.9273 | 0.8506 | 0.9719 | |
| UACC-893 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.00213 | uM | 9045.001 | 1.1716 | 1.3540 | 0.9719 | |
| UACC-893 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0107 | uM | 9045.001 | 0.9561 | 0.9096 | 0.9719 | |
| UACC-893 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0533 | uM | 9045.001 | 0.9773 | 0.9534 | 0.9719 | |
| UACC-893 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.267 | uM | 9045.001 | 0.8298 | 0.6506 | 0.9719 | |
| UACC-893 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 1.33 | uM | 9045.001 | 0.9457 | 0.8884 | 0.9719 | |
| UACC-893 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 6.67 | uM | 9045.001 | 0.8554 | 0.7031 | 0.9719 | |
| UACC-893 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 33.3 | uM | 9045.001 | 0.5057 | -0.0084 | 0.9719 | |
| UACC-893 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0000853 | uM | 9933.001 | 1.1193 | 1.5628 | 0.4544 | |
| UACC-893 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.000427 | uM | 9933.001 | 0.9377 | 0.7362 | 0.4544 | |
| UACC-893 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.00213 | uM | 9933.001 | 1.0827 | 1.3822 | 0.4544 | |
| UACC-893 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0107 | uM | 9933.001 | 0.9779 | 0.9038 | 0.4544 | |
| UACC-893 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0533 | uM | 9933.001 | 1.0838 | 1.3876 | 0.4544 | |
| UACC-893 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.267 | uM | 9933.001 | 0.9357 | 0.7279 | 0.4544 | |
| UACC-893 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 1.33 | uM | 9933.001 | 0.9765 | 0.8982 | 0.4544 | |
| UACC-893 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 6.67 | uM | 9933.001 | 0.8982 | 0.5790 | 0.4544 | |
| UACC-893 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 33.3 | uM | 9933.001 | 0.7135 | -0.0485 | 0.4544 | |
| UACC-893 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0000853 | uM | 9953.001 | 1.1417 | 1.9613 | 0.3377 | |
| UACC-893 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.000427 | uM | 9953.001 | 0.9398 | 0.6642 | 0.3377 | |
| UACC-893 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.00213 | uM | 9953.001 | 1.1415 | 1.9595 | 0.3377 | |
| UACC-893 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0107 | uM | 9953.001 | 0.9396 | 0.6629 | 0.3377 |