Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-157	TNBC	Basal B	GSK1070916	AURK	AURK	0.00213	uM	10093.001	0.9705	0.8987	0.5759
MDA-MB-157	TNBC	Basal B	GSK1070916	AURK	AURK	0.0107	uM	10093.001	0.8351	0.4627	0.5759
MDA-MB-157	TNBC	Basal B	GSK1070916	AURK	AURK	0.0533	uM	10093.001	0.2316	-0.8422	0.5759
MDA-MB-157	TNBC	Basal B	GSK1070916	AURK	AURK	0.267	uM	10093.001	0.6149	-0.1404	0.5759
MDA-MB-157	TNBC	Basal B	GSK1070916	AURK	AURK	1.33	uM	10093.001	0.5981	-0.1809	0.5759
MDA-MB-157	TNBC	Basal B	GSK1070916	AURK	AURK	6.67	uM	10093.001	0.3917	-0.6071	0.5759
MDA-MB-157	TNBC	Basal B	GSK1070916	AURK	AURK	33.3	uM	10093.001	0.0112	-0.9992	0.5759
MDA-MB-175-VII	HR+	Luminal	GSK1070916	AURK	AURK	0.0000853	uM	7884.001	1.0686	1.2635	0.5364
MDA-MB-175-VII	HR+	Luminal	GSK1070916	AURK	AURK	0.000427	uM	7884.001	0.9841	0.9413	0.5364
MDA-MB-175-VII	HR+	Luminal	GSK1070916	AURK	AURK	0.00213	uM	7884.001	0.9998	0.9993	0.5364
MDA-MB-175-VII	HR+	Luminal	GSK1070916	AURK	AURK	0.0107	uM	7884.001	0.9140	0.6913	0.5364
MDA-MB-175-VII	HR+	Luminal	GSK1070916	AURK	AURK	0.0533	uM	7884.001	0.9471	0.8071	0.5364
MDA-MB-175-VII	HR+	Luminal	GSK1070916	AURK	AURK	0.267	uM	7884.001	0.8835	0.5876	0.5364
MDA-MB-175-VII	HR+	Luminal	GSK1070916	AURK	AURK	1.33	uM	7884.001	0.9133	0.6888	0.5364
MDA-MB-175-VII	HR+	Luminal	GSK1070916	AURK	AURK	6.67	uM	7884.001	0.8343	0.4267	0.5364
MDA-MB-175-VII	HR+	Luminal	GSK1070916	AURK	AURK	33.3	uM	7884.001	0.0909	-0.9771	0.5364
MDA-MB-175-VII	HR+	Luminal	GSK1070916	AURK	AURK	0.0000853	uM	7885.001	1.0177	1.0567	0.6265
MDA-MB-175-VII	HR+	Luminal	GSK1070916	AURK	AURK	0.000427	uM	7885.001	1.0214	1.0687	0.6265
MDA-MB-175-VII	HR+	Luminal	GSK1070916	AURK	AURK	0.00213	uM	7885.001	1.0906	1.2970	0.6265
MDA-MB-175-VII	HR+	Luminal	GSK1070916	AURK	AURK	0.0107	uM	7885.001	0.9395	0.8104	0.6265
MDA-MB-175-VII	HR+	Luminal	GSK1070916	AURK	AURK	0.0533	uM	7885.001	1.0114	1.0367	0.6265
MDA-MB-175-VII	HR+	Luminal	GSK1070916	AURK	AURK	0.267	uM	7885.001	0.9858	0.9547	0.6265
MDA-MB-175-VII	HR+	Luminal	GSK1070916	AURK	AURK	1.33	uM	7885.001	0.9999	0.9998	0.6265
MDA-MB-175-VII	HR+	Luminal	GSK1070916	AURK	AURK	6.67	uM	7885.001	0.9813	0.9406	0.6265
MDA-MB-175-VII	HR+	Luminal	GSK1070916	AURK	AURK	33.3	uM	7885.001	0.4228	-0.4939	0.6265

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)