Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 0.000427 | uM | 7872.001 | 0.8596 | 0.7896 | 1.3610 | |
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 0.00213 | uM | 7872.001 | 1.0404 | 1.0591 | 1.3610 | |
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 0.0107 | uM | 7872.001 | 0.8588 | 0.7884 | 1.3610 | |
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 0.0533 | uM | 7872.001 | 0.8793 | 0.8196 | 1.3610 | |
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 0.267 | uM | 7872.001 | 0.8408 | 0.7607 | 1.3610 | |
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 1.33 | uM | 7872.001 | 0.8109 | 0.7145 | 1.3610 | |
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 6.67 | uM | 7872.001 | 0.4360 | 0.0867 | 1.3610 | |
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 33.3 | uM | 7872.001 | 0.0798 | -0.6879 | 1.3610 | |
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 0.0000853 | uM | 9566.001 | 1.0217 | 1.0204 | 2.1122 | |
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 0.000427 | uM | 9566.001 | 1.0244 | 1.0229 | 2.1122 | |
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 0.00213 | uM | 9566.001 | 1.0481 | 1.0450 | 2.1122 | |
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 0.0107 | uM | 9566.001 | 1.0260 | 1.0245 | 2.1122 | |
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 0.0533 | uM | 9566.001 | 0.8072 | 0.8071 | 2.1122 | |
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 0.267 | uM | 9566.001 | 0.8336 | 0.8349 | 2.1122 | |
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 1.33 | uM | 9566.001 | 0.8203 | 0.8210 | 2.1122 | |
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 6.67 | uM | 9566.001 | 0.5942 | 0.5631 | 2.1122 | |
| MCF 10F | NM | - | GSK1070916 | AURK | AURK | 33.3 | uM | 9566.001 | 0.0992 | -0.3303 | 2.1122 | |
| MCF12A | NM | Basal B | GSK1070916 | AURK | AURK | 0.0000853 | uM | 10061.001 | 1.0304 | 1.0347 | 1.7406 | |
| MCF12A | NM | Basal B | GSK1070916 | AURK | AURK | 0.000427 | uM | 10061.001 | 1.0215 | 1.0246 | 1.7406 | |
| MCF12A | NM | Basal B | GSK1070916 | AURK | AURK | 0.00213 | uM | 10061.001 | 1.0747 | 1.0845 | 1.7406 | |
| MCF12A | NM | Basal B | GSK1070916 | AURK | AURK | 0.0107 | uM | 10061.001 | 0.8852 | 0.8646 | 1.7406 | |
| MCF12A | NM | Basal B | GSK1070916 | AURK | AURK | 0.0533 | uM | 10061.001 | 0.8554 | 0.8283 | 1.7406 | |
| MCF12A | NM | Basal B | GSK1070916 | AURK | AURK | 0.267 | uM | 10061.001 | 0.8336 | 0.8015 | 1.7406 | |
| MCF12A | NM | Basal B | GSK1070916 | AURK | AURK | 1.33 | uM | 10061.001 | 0.8604 | 0.8345 | 1.7406 | |
| MCF12A | NM | Basal B | GSK1070916 | AURK | AURK | 6.67 | uM | 10061.001 | 0.6693 | 0.5880 | 1.7406 |