Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0000853 | uM | 9501.001 | 1.0795 | 1.1595 | 0.9969 | |
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.000427 | uM | 9501.001 | 1.0716 | 1.1437 | 0.9969 | |
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.00213 | uM | 9501.001 | 1.0759 | 1.1523 | 0.9969 | |
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0107 | uM | 9501.001 | 0.9135 | 0.8266 | 0.9969 | |
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0533 | uM | 9501.001 | 0.6912 | 0.3808 | 0.9969 | |
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.267 | uM | 9501.001 | 0.7565 | 0.5117 | 0.9969 | |
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 1.33 | uM | 9501.001 | 0.6736 | 0.3456 | 0.9969 | |
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 6.67 | uM | 9501.001 | 0.3955 | -0.2113 | 0.9969 | |
| HCC70 | TNBC | Basal A | GSK1070916 | AURK | AURK | 33.3 | uM | 9501.001 | 0.0275 | -0.9456 | 0.9969 | |
| HMT-3522 S1 | Unknown | Unknown | GSK1070916 | AURK | AURK | 0.0000853 | uM | 7911.001 | 0.6962 | 0.4792 | 1.2005 | |
| HMT-3522 S1 | Unknown | Unknown | GSK1070916 | AURK | AURK | 0.000427 | uM | 7911.001 | 1.0952 | 1.1573 | 1.2005 | |
| HMT-3522 S1 | Unknown | Unknown | GSK1070916 | AURK | AURK | 0.00213 | uM | 7911.001 | 1.0856 | 1.1416 | 1.2005 | |
| HMT-3522 S1 | Unknown | Unknown | GSK1070916 | AURK | AURK | 0.0107 | uM | 7911.001 | 0.9168 | 0.8603 | 1.2005 | |
| HMT-3522 S1 | Unknown | Unknown | GSK1070916 | AURK | AURK | 0.0533 | uM | 7911.001 | 0.8903 | 0.8155 | 1.2005 | |
| HMT-3522 S1 | Unknown | Unknown | GSK1070916 | AURK | AURK | 0.267 | uM | 7911.001 | 0.5789 | 0.2684 | 1.2005 | |
| HMT-3522 S1 | Unknown | Unknown | GSK1070916 | AURK | AURK | 1.33 | uM | 7911.001 | 0.6732 | 0.4384 | 1.2005 | |
| HMT-3522 S1 | Unknown | Unknown | GSK1070916 | AURK | AURK | 6.67 | uM | 7911.001 | 0.3694 | -0.1275 | 1.2005 | |
| HMT-3522 S1 | Unknown | Unknown | GSK1070916 | AURK | AURK | 33.3 | uM | 7911.001 | 0.0096 | -0.9585 | 1.2005 | |
| HMT-3522 S1 | Unknown | Unknown | GSK1070916 | AURK | AURK | 0.0000853 | uM | 10124.001 | 1.1443 | 1.1272 | 2.1861 | |
| HMT-3522 S1 | Unknown | Unknown | GSK1070916 | AURK | AURK | 0.000427 | uM | 10124.001 | 0.7658 | 0.7702 | 2.1861 | |
| HMT-3522 S1 | Unknown | Unknown | GSK1070916 | AURK | AURK | 0.00213 | uM | 10124.001 | 1.0157 | 1.0143 | 2.1861 | |
| HMT-3522 S1 | Unknown | Unknown | GSK1070916 | AURK | AURK | 0.0107 | uM | 10124.001 | 0.8739 | 0.8804 | 2.1861 | |
| HMT-3522 S1 | Unknown | Unknown | GSK1070916 | AURK | AURK | 0.0533 | uM | 10124.001 | 0.9057 | 0.9114 | 2.1861 | |
| HMT-3522 S1 | Unknown | Unknown | GSK1070916 | AURK | AURK | 0.267 | uM | 10124.001 | 0.7586 | 0.7626 | 2.1861 | |
| HMT-3522 S1 | Unknown | Unknown | GSK1070916 | AURK | AURK | 1.33 | uM | 10124.001 | 0.4632 | 0.4065 | 2.1861 |