Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.00213 | uM | 7820.001 | 1.0269 | 1.0703 | 0.7692 | |
| HCC1419 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0107 | uM | 7820.001 | 0.9731 | 0.9302 | 0.7692 | |
| HCC1419 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0533 | uM | 7820.001 | 0.9819 | 0.9530 | 0.7692 | |
| HCC1419 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.267 | uM | 7820.001 | 0.9997 | 0.9993 | 0.7692 | |
| HCC1419 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 1.33 | uM | 7820.001 | 1.0442 | 1.1156 | 0.7692 | |
| HCC1419 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 6.67 | uM | 7820.001 | 0.8494 | 0.6175 | 0.7692 | |
| HCC1419 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 33.3 | uM | 7820.001 | 0.7169 | 0.2975 | 0.7692 | |
| HCC1419 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0000853 | uM | 7821.001 | 1.0381 | 1.2406 | 0.3296 | |
| HCC1419 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.000427 | uM | 7821.001 | 1.0201 | 1.1243 | 0.3296 | |
| HCC1419 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.00213 | uM | 7821.001 | 1.0078 | 1.0477 | 0.3296 | |
| HCC1419 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0107 | uM | 7821.001 | 0.9689 | 0.8171 | 0.3296 | |
| HCC1419 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0533 | uM | 7821.001 | 1.0388 | 1.2451 | 0.3296 | |
| HCC1419 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.267 | uM | 7821.001 | 1.0155 | 1.0956 | 0.3296 | |
| HCC1419 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 1.33 | uM | 7821.001 | 1.0231 | 1.1434 | 0.3296 | |
| HCC1419 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 6.67 | uM | 7821.001 | 0.8397 | 0.1771 | 0.3296 | |
| HCC1419 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 33.3 | uM | 7821.001 | 0.6597 | -0.4340 | 0.3296 | |
| HCC1419 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0000853 | uM | 9278.001 | 1.0759 | 1.3591 | 0.4429 | |
| HCC1419 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.000427 | uM | 9278.001 | 1.0120 | 1.0545 | 0.4429 | |
| HCC1419 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.00213 | uM | 9278.001 | 1.0290 | 1.1332 | 0.4429 | |
| HCC1419 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0107 | uM | 9278.001 | 0.9804 | 0.9124 | 0.4429 | |
| HCC1419 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0533 | uM | 9278.001 | 1.0061 | 1.0279 | 0.4429 | |
| HCC1419 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.267 | uM | 9278.001 | 0.9469 | 0.7683 | 0.4429 | |
| HCC1419 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 1.33 | uM | 9278.001 | 1.0133 | 1.0604 | 0.4429 | |
| HCC1419 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 6.67 | uM | 9278.001 | 0.8760 | 0.4833 | 0.4429 | |
| HCC1419 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 33.3 | uM | 9278.001 | 0.6879 | -0.1408 | 0.4429 |