Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0000853 | uM | 9035.001 | 0.9353 | 0.9457 | 2.4291 | |
| AU565 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.000427 | uM | 9035.001 | 1.1130 | 1.0901 | 2.4291 | |
| AU565 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.00213 | uM | 9035.001 | 0.9295 | 0.9407 | 2.4291 | |
| AU565 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0107 | uM | 9035.001 | 0.7709 | 0.7969 | 2.4291 | |
| AU565 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0533 | uM | 9035.001 | 0.6085 | 0.6301 | 2.4291 | |
| AU565 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.267 | uM | 9035.001 | 0.6262 | 0.6495 | 2.4291 | |
| AU565 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 1.33 | uM | 9035.001 | 0.7081 | 0.7351 | 2.4291 | |
| AU565 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 6.67 | uM | 9035.001 | 0.5385 | 0.5501 | 2.4291 | |
| AU565 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 33.3 | uM | 9035.001 | 0.2464 | 0.1236 | 2.4291 | |
| AU565 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0000853 | uM | 9146.001 | 0.9027 | 0.8471 | 1.2878 | |
| AU565 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.000427 | uM | 9146.001 | 0.9477 | 0.9183 | 1.2878 | |
| AU565 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.00213 | uM | 9146.001 | 0.9862 | 0.9786 | 1.2878 | |
| AU565 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0107 | uM | 9146.001 | 0.8541 | 0.7695 | 1.2878 | |
| AU565 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0533 | uM | 9146.001 | 0.7645 | 0.6236 | 1.2878 | |
| AU565 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.267 | uM | 9146.001 | 0.7630 | 0.6211 | 1.2878 | |
| AU565 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 1.33 | uM | 9146.001 | 0.8712 | 0.7970 | 1.2878 | |
| AU565 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 6.67 | uM | 9146.001 | 0.5468 | 0.2516 | 1.2878 | |
| AU565 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 33.3 | uM | 9146.001 | 0.1142 | -0.6291 | 1.2878 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0000853 | uM | 7798.001 | 1.0409 | 1.0595 | 1.3667 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.000427 | uM | 7798.001 | 1.0277 | 1.0404 | 1.3667 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.00213 | uM | 7798.001 | 1.0447 | 1.0650 | 1.3667 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0107 | uM | 7798.001 | 0.9467 | 0.9215 | 1.3667 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0533 | uM | 7798.001 | 1.0287 | 1.0418 | 1.3667 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.267 | uM | 7798.001 | 0.9461 | 0.9205 | 1.3667 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 1.33 | uM | 7798.001 | 0.9604 | 0.9418 | 1.3667 |