Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 6.67 | uM | 7798.001 | 0.8185 | 0.7274 | 1.3667 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 33.3 | uM | 7798.001 | 0.3308 | -0.1098 | 1.3667 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0000853 | uM | 9157.001 | 1.0677 | 1.1475 | 0.9211 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.000427 | uM | 9157.001 | 1.0211 | 1.0459 | 0.9211 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.00213 | uM | 9157.001 | 1.0738 | 1.1607 | 0.9211 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0107 | uM | 9157.001 | 0.9891 | 0.9764 | 0.9211 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0533 | uM | 9157.001 | 1.0174 | 1.0378 | 0.9211 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.267 | uM | 9157.001 | 1.0141 | 1.0306 | 0.9211 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 1.33 | uM | 9157.001 | 0.9444 | 0.8795 | 0.9211 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 6.67 | uM | 9157.001 | 0.7951 | 0.5593 | 0.9211 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 33.3 | uM | 9157.001 | 0.2459 | -0.5639 | 0.9211 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0000853 | uM | 9158.001 | 0.9835 | 0.9528 | 0.6988 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.000427 | uM | 9158.001 | 0.9640 | 0.8978 | 0.6988 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.00213 | uM | 9158.001 | 1.0048 | 1.0138 | 0.6988 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0107 | uM | 9158.001 | 0.9414 | 0.8345 | 0.6988 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0533 | uM | 9158.001 | 1.0048 | 1.0138 | 0.6988 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.267 | uM | 9158.001 | 1.0094 | 1.0270 | 0.6988 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 1.33 | uM | 9158.001 | 0.9783 | 0.9382 | 0.6988 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 6.67 | uM | 9158.001 | 0.7309 | 0.2771 | 0.6988 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 33.3 | uM | 9158.001 | 0.0466 | -0.9752 | 0.6988 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0000853 | uM | 9163.001 | 1.0290 | 1.1125 | 0.5227 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.000427 | uM | 9163.001 | 1.0775 | 1.3069 | 0.5227 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.00213 | uM | 9163.001 | 1.0490 | 1.1915 | 0.5227 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0107 | uM | 9163.001 | 0.9911 | 0.9660 | 0.5227 | |
| BT-474 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0533 | uM | 9163.001 | 1.0082 | 1.0316 | 0.5227 |