Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 7862.016 | 1.0294 | 1.0444 | 1.3229 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 7862.016 | 0.9920 | 0.9879 | 1.3229 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 7862.016 | 0.5683 | 0.3047 | 1.3229 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7863.016 | 1.0238 | 1.0268 | 1.7699 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7863.016 | 1.0030 | 1.0034 | 1.7699 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7863.016 | 1.0096 | 1.0108 | 1.7699 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7863.016 | 0.9702 | 0.9661 | 1.7699 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7863.016 | 0.9509 | 0.9439 | 1.7699 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 7863.016 | 0.9584 | 0.9526 | 1.7699 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 7863.016 | 0.9688 | 0.9645 | 1.7699 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 7863.016 | 0.9609 | 0.9554 | 1.7699 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 7863.016 | 0.4181 | 0.2219 | 1.7699 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7864.016 | 0.9441 | 0.9242 | 1.4893 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7864.016 | 0.9530 | 0.9364 | 1.4893 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7864.016 | 0.9556 | 0.9400 | 1.4893 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7864.016 | 0.9861 | 0.9813 | 1.4893 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7864.016 | 0.9530 | 0.9364 | 1.4893 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 7864.016 | 1.0591 | 1.0786 | 1.4893 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 7864.016 | 0.9812 | 0.9747 | 1.4893 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 7864.016 | 0.9771 | 0.9692 | 1.4893 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 7864.016 | 0.6665 | 0.5230 | 1.4893 | |
| LY2 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7865.016 | 1.1237 | 1.1335 | 1.8047 | |
| LY2 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7865.016 | 1.1936 | 1.2061 | 1.8047 | |
| LY2 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7865.016 | 1.2215 | 1.2345 | 1.8047 | |
| LY2 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7865.016 | 1.2542 | 1.2674 | 1.8047 |