Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 33.3 | uM | 7829.016 | 0.2974 | 0.0749 | 1.9532 | |
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7830.016 | 0.8836 | 0.8818 | 2.0313 | |
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7830.016 | 0.9881 | 0.9882 | 2.0313 | |
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7830.016 | 0.8350 | 0.8301 | 2.0313 | |
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7830.016 | 0.9063 | 0.9055 | 2.0313 | |
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7830.016 | 0.9116 | 0.9109 | 2.0313 | |
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.267 | uM | 7830.016 | 0.8216 | 0.8156 | 2.0313 | |
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 1.33 | uM | 7830.016 | 0.7079 | 0.6873 | 2.0313 | |
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 6.67 | uM | 7830.016 | 0.6592 | 0.6291 | 2.0313 | |
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 33.3 | uM | 7830.016 | 0.1252 | -0.2809 | 2.0313 | |
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9376.024 | 1.0295 | 1.0338 | 1.7329 | |
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9376.024 | 0.9853 | 0.9829 | 1.7329 | |
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9376.024 | 1.0770 | 1.0875 | 1.7329 | |
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9376.024 | 0.8631 | 0.8371 | 1.7329 | |
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9376.024 | 0.9619 | 0.9556 | 1.7329 | |
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.267 | uM | 9376.024 | 0.8409 | 0.8096 | 1.7329 | |
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 1.33 | uM | 9376.024 | 0.8039 | 0.7633 | 1.7329 | |
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 6.67 | uM | 9376.024 | 0.6548 | 0.5665 | 1.7329 | |
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 33.3 | uM | 9376.024 | 0.2770 | -0.0465 | 1.7329 | |
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9376.049 | 1.0480 | 1.0494 | 1.9229 | |
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9376.049 | 0.9208 | 0.9160 | 1.9229 | |
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9376.049 | 1.0197 | 1.0204 | 1.9229 | |
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9376.049 | 0.9292 | 0.9250 | 1.9229 | |
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9376.049 | 0.8673 | 0.8573 | 1.9229 | |
| HCC1806 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.267 | uM | 9376.049 | 0.6433 | 0.5900 | 1.9229 |