Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 33.3 | uM | 9501.024 | 0.0302 | -0.9558 | 0.9185 | |
| HMT-3522 S1 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7911.016 | 1.0279 | 1.0417 | 1.3310 | |
| HMT-3522 S1 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7911.016 | 1.0729 | 1.1086 | 1.3310 | |
| HMT-3522 S1 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7911.016 | 1.0401 | 1.0600 | 1.3310 | |
| HMT-3522 S1 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7911.016 | 1.0075 | 1.0112 | 1.3310 | |
| HMT-3522 S1 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7911.016 | 0.9546 | 0.9314 | 1.3310 | |
| HMT-3522 S1 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 0.267 | uM | 7911.016 | 0.6770 | 0.4919 | 1.3310 | |
| HMT-3522 S1 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 1.33 | uM | 7911.016 | 0.4036 | 0.0114 | 1.3310 | |
| HMT-3522 S1 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 6.67 | uM | 7911.016 | 0.3932 | -0.0081 | 1.3310 | |
| HMT-3522 S1 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 33.3 | uM | 7911.016 | 0.2313 | -0.3343 | 1.3310 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7861.016 | 0.9021 | 0.9018 | 2.0473 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7861.016 | 0.8962 | 0.8958 | 2.0473 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7861.016 | 0.8799 | 0.8789 | 2.0473 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7861.016 | 0.9031 | 0.9028 | 2.0473 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7861.016 | 0.8508 | 0.8482 | 2.0473 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 7861.016 | 0.8767 | 0.8755 | 2.0473 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 7861.016 | 0.9173 | 0.9174 | 2.0473 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 7861.016 | 0.7469 | 0.7344 | 2.0473 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 7861.016 | 0.0380 | -0.5950 | 2.0473 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7862.016 | 1.0393 | 1.0591 | 1.3229 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7862.016 | 0.9368 | 0.9037 | 1.3229 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7862.016 | 1.0768 | 1.1151 | 1.3229 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7862.016 | 0.9830 | 0.9743 | 1.3229 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7862.016 | 0.9643 | 0.9457 | 1.3229 | |
| Hs 578T | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 7862.016 | 0.9990 | 0.9985 | 1.3229 |