Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
SUM1315MO2	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	13.3	uM	12428.167	0.8767	0.7573	1.0169
SUM1315MO2	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	66.7	uM	12428.167	0.7862	0.5788	1.0169
SUM149PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	0.0000853	uM	10819.154	0.9553	0.9563	2.0680
SUM149PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	0.000427	uM	10819.154	1.0031	1.0030	2.0680
SUM149PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	0.00213	uM	10819.154	0.9846	0.9850	2.0680
SUM149PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	0.0107	uM	10819.154	0.9980	0.9981	2.0680
SUM149PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	0.0533	uM	10819.154	1.0234	1.0225	2.0680
SUM149PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	0.267	uM	10819.154	0.9636	0.9644	2.0680
SUM149PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	1.33	uM	10819.154	0.9393	0.9403	2.0680
SUM149PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	6.67	uM	10819.154	1.0308	1.0296	2.0680
SUM149PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	33.3	uM	10819.154	0.5088	0.4426	2.0680
SUM149PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	0.0000853	uM	11937.154	0.9036	0.9214	2.5304
SUM149PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	0.000427	uM	11937.154	0.8775	0.8993	2.5304
SUM149PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	0.00213	uM	11937.154	0.9260	0.9402	2.5304
SUM149PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	0.0107	uM	11937.154	0.9240	0.9385	2.5304
SUM149PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	0.0533	uM	11937.154	0.9737	0.9790	2.5304
SUM149PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	0.267	uM	11937.154	0.8869	0.9074	2.5304
SUM149PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	1.33	uM	11937.154	0.9547	0.9637	2.5304
SUM149PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	6.67	uM	11937.154	0.8820	0.9032	2.5304
SUM149PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	33.3	uM	11937.154	0.2548	0.1651	2.5304
SUM159PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	0.0000853	uM	10520.142	0.9820	0.9886	3.1766
SUM159PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	0.000427	uM	10520.142	0.9740	0.9835	3.1766
SUM159PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	0.00213	uM	10520.142	1.0569	1.0351	3.1766
SUM159PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	0.0107	uM	10520.142	1.1775	1.1056	3.1766
SUM159PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	0.0533	uM	10520.142	0.8501	0.9003	3.1766

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)