Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0000853 | uM | 11851.154 | 0.9591 | 0.9302 | 1.1765 | |
| SK-BR-3 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.000427 | uM | 11851.154 | 0.9868 | 0.9776 | 1.1765 | |
| SK-BR-3 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.00213 | uM | 11851.154 | 1.0208 | 1.0353 | 1.1765 | |
| SK-BR-3 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0107 | uM | 11851.154 | 0.9510 | 0.9164 | 1.1765 | |
| SK-BR-3 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0533 | uM | 11851.154 | 0.9856 | 0.9756 | 1.1765 | |
| SK-BR-3 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.267 | uM | 11851.154 | 0.9674 | 0.9445 | 1.1765 | |
| SK-BR-3 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 1.33 | uM | 11851.154 | 1.0230 | 1.0391 | 1.1765 | |
| SK-BR-3 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 6.67 | uM | 11851.154 | 0.9983 | 0.9971 | 1.1765 | |
| SK-BR-3 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 33.3 | uM | 11851.154 | 1.0416 | 1.0704 | 1.1765 | |
| SUM1315MO2 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.0000853 | uM | 10875.154 | 1.0186 | 1.0522 | 0.7163 | |
| SUM1315MO2 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.000427 | uM | 10875.154 | 1.0953 | 1.2709 | 0.7163 | |
| SUM1315MO2 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.00213 | uM | 10875.154 | 1.0064 | 1.0179 | 0.7163 | |
| SUM1315MO2 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.0107 | uM | 10875.154 | 1.0271 | 1.0760 | 0.7163 | |
| SUM1315MO2 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.0533 | uM | 10875.154 | 1.0342 | 1.0962 | 0.7163 | |
| SUM1315MO2 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.267 | uM | 10875.154 | 0.9854 | 0.9594 | 0.7163 | |
| SUM1315MO2 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 1.33 | uM | 10875.154 | 1.0253 | 1.0709 | 0.7163 | |
| SUM1315MO2 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 6.67 | uM | 10875.154 | 0.9742 | 0.9282 | 0.7163 | |
| SUM1315MO2 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 33.3 | uM | 10875.154 | 0.8138 | 0.4999 | 0.7163 | |
| SUM1315MO2 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.000171 | uM | 12428.167 | 0.9786 | 0.9578 | 1.0169 | |
| SUM1315MO2 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.000853 | uM | 12428.167 | 0.9899 | 0.9802 | 1.0169 | |
| SUM1315MO2 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.00427 | uM | 12428.167 | 1.0171 | 1.0337 | 1.0169 | |
| SUM1315MO2 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.0213 | uM | 12428.167 | 0.9536 | 0.9086 | 1.0169 | |
| SUM1315MO2 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.107 | uM | 12428.167 | 0.9585 | 0.9184 | 1.0169 | |
| SUM1315MO2 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.533 | uM | 12428.167 | 0.9909 | 0.9822 | 1.0169 | |
| SUM1315MO2 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 2.67 | uM | 12428.167 | 0.9428 | 0.8875 | 1.0169 |