Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-549 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 13.3 | uM | 12305.167 | 0.9885 | 0.9920 | 2.8814 | |
| BT-549 | TNBC | Basal B | FTase Inhibitor I | Ftase | MAPK | 66.7 | uM | 12305.167 | 0.9330 | 0.9525 | 2.8814 | |
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0000853 | uM | 10473.142 | 0.9647 | 0.9346 | 1.0815 | |
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.000427 | uM | 10473.142 | 0.9774 | 0.9582 | 1.0815 | |
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.00213 | uM | 10473.142 | 0.9500 | 0.9073 | 1.0815 | |
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0107 | uM | 10473.142 | 0.9868 | 0.9756 | 1.0815 | |
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0533 | uM | 10473.142 | 0.9985 | 0.9973 | 1.0815 | |
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.267 | uM | 10473.142 | 0.9398 | 0.8883 | 1.0815 | |
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 1.33 | uM | 10473.142 | 1.0184 | 1.0339 | 1.0815 | |
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 6.67 | uM | 10473.142 | 0.9691 | 0.9428 | 1.0815 | |
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 33.3 | uM | 10473.142 | 0.9967 | 0.9940 | 1.0815 | |
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0000853 | uM | 10755.154 | 0.9153 | 0.8338 | 1.0198 | |
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.000427 | uM | 10755.154 | 0.8753 | 0.7551 | 1.0198 | |
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.00213 | uM | 10755.154 | 0.9056 | 0.8147 | 1.0198 | |
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0107 | uM | 10755.154 | 0.9038 | 0.8112 | 1.0198 | |
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0533 | uM | 10755.154 | 0.9543 | 0.9104 | 1.0198 | |
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.267 | uM | 10755.154 | 0.9448 | 0.8916 | 1.0198 | |
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 1.33 | uM | 10755.154 | 0.9887 | 0.9779 | 1.0198 | |
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 6.67 | uM | 10755.154 | 0.9148 | 0.8328 | 1.0198 | |
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 33.3 | uM | 10755.154 | 0.9325 | 0.8676 | 1.0198 | |
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0000853 | uM | 12070.154 | 0.9329 | 0.8777 | 1.1006 | |
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.000427 | uM | 12070.154 | 0.9822 | 0.9676 | 1.1006 | |
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.00213 | uM | 12070.154 | 0.9922 | 0.9858 | 1.1006 | |
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0107 | uM | 12070.154 | 0.9224 | 0.8585 | 1.1006 | |
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0533 | uM | 12070.154 | 0.9907 | 0.9831 | 1.1006 |