Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 9583.012 | 0.6384 | 0.3530 | 1.1482 | |
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 4 | uM | 9583.012 | 0.6397 | 0.3554 | 1.1482 | |
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 20 | uM | 9583.012 | 0.6508 | 0.3757 | 1.1482 | |
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 100 | uM | 9583.012 | 0.5440 | 0.1770 | 1.1482 | |
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 10073.012 | 0.9943 | 0.9800 | 0.5734 | |
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 10073.012 | 1.0211 | 1.0741 | 0.5734 | |
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 10073.012 | 1.0051 | 1.0177 | 0.5734 | |
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 10073.012 | 1.0436 | 1.1545 | 0.5734 | |
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 10073.012 | 1.0259 | 1.0913 | 0.5734 | |
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 10073.012 | 0.9087 | 0.6925 | 0.5734 | |
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 4 | uM | 10073.012 | 0.8798 | 0.5997 | 0.5734 | |
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 20 | uM | 10073.012 | 0.7236 | 0.1375 | 0.5734 | |
| MCF7 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 100 | uM | 10073.012 | 0.7169 | 0.1193 | 0.5734 | |
| MDA-MB-134-VI | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 7876.04 | 1.0157 | 1.0288 | 1.0852 | |
| MDA-MB-134-VI | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 7876.04 | 1.0182 | 1.0335 | 1.0852 | |
| MDA-MB-134-VI | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 7876.04 | 0.9762 | 0.9561 | 1.0852 | |
| MDA-MB-134-VI | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 7876.04 | 0.2501 | -0.4424 | 1.0852 | |
| MDA-MB-134-VI | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 7876.04 | 0.1556 | -0.6398 | 1.0852 | |
| MDA-MB-134-VI | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 7876.04 | 0.1430 | -0.6669 | 1.0852 | |
| MDA-MB-134-VI | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 4 | uM | 7876.04 | 0.1322 | -0.6902 | 1.0852 | |
| MDA-MB-134-VI | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 20 | uM | 7876.04 | 0.1497 | -0.6524 | 1.0852 | |
| MDA-MB-134-VI | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 100 | uM | 7876.04 | 0.1339 | -0.6865 | 1.0852 | |
| MDA-MB-134-VI | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 10077.049 | 1.0630 | 1.2376 | 0.5440 | |
| MDA-MB-134-VI | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 10077.049 | 1.1556 | 1.6093 | 0.5440 | |
| MDA-MB-134-VI | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 10077.049 | 1.0421 | 1.1574 | 0.5440 |