Highly-multiplexed imaging by Cyclic Immunofluorescence (CycIF) of protein levels and protein phosphorylation states in the MCF 10A breast cell line treated with EGF or four kinase inhibitors - Dataset (ID:20267)
- Detail
- Small Molecules Studied
- Cell Lines Studied
- Proteins Studied
- Antibodies Studied
- Other Reagents Studied
- Results
Proteins Studied
Download: Excel (XLSX), Comma-separated (CSV)
| LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
|---|---|---|---|---|---|---|---|---|---|
| 201339 | Aurora kinase A (pT288) | 201339 | O14965 | pT288 | |||||
| 201350 | FOXO3a | 201350 | O43524 | Forkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1 | |||||
| 200507 | EGFR | 200507 | P00533 | Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1 | |||||
| 201357 | EGF | 201357 | P01133 | Epidermal Growth Factor; Urogastrone; URG | PeproTech | ||||
| 201307 | K6A | 201307 | P02538 | Keratin, type II cytoskeletal 6A; Cytokeratin-6A; CK-6A; Cytokeratin-6D; CK-6D; Keratin-6A; Type-II keratin Kb6; Hom s 5 | |||||
| 201308 | K6B | 201308 | P04259 | Keratin, type II cytoskeletal 6B; Cytokeratin-6B; CK-6B; Keratin-6B; Type-II keratin Kb10 | |||||
| 200543 | p53 | 200543 | P04637 | Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53 | |||||
| 201313 | K18 | 201313 | P05783 | Keratin, type I cytoskeletal 18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18 | |||||
| 201310 | K8 | 201310 | P05787 | Keratin, type II cytoskeletal 8; Cytokeratin-8; CK-8; Type-II keratin Kb8 | |||||
| 201335 | Rb (pS807) | 201335 | P06400 | pS807 | |||||
| 201336 | Rb (pS811) | 201336 | P06400 | pS811 | |||||
| 201297 | Rb (pS807; pS811) | 201297 | P06400 | pS807; pS811 | |||||
| 201348 | Vimentin | 201348 | P08670 | ||||||
| 201343 | PARP-1 (D214-cleaved) | 201343 | P09874 | D214-cleaved | |||||
| 201302 | PCNA | 201302 | P12004 | Proliferating cell nuclear antigen; Cyclin | |||||
| 201353 | E-cadherin | 201353 | P12830 | CAM 120/80; Epithelial cadherin; E-cadherin; Uvomorulin; CD324 | |||||
| 201311 | K10 | 201311 | P13645 | Keratin, type I cytoskeletal 10; Cytokeratin-10; CK-10 | |||||
| 201312 | K13 | 201312 | P13646 | Keratin, type I cytoskeletal 13; Cytokeratin-13; CK-13 | |||||
| 201306 | K5 | 201306 | P13647 | Keratin, type II cytoskeletal 5; 58 kDa cytokeratin; Cytokeratin-5; CK-5; Keratin-5; Type-II keratin Kb5 | |||||
| 201314 | H2A.X (pS139) | 201314 | P16104 | pS139 | |||||
| 201305 | K4 | 201305 | P19013 | Keratin, type II cytoskeletal 4; Cytokeratin-4; CK-4; Keratin-4; Type-II keratin Kb4 | |||||
| 201351 | Cyclin-D1 | 201351 | P24385 | G1/S-specific cyclin-D1; B-cell lymphoma 1 protein; BCL-1; BCL-1 oncogene; PRAD1 oncogene | |||||
| 201337 | ERK-1 (pT202) | 201337 | P27361 | pT202 | |||||
| 201303 | ERK-1 (pT202; pY204) | 201303 | P27361 | pT202; pY204 | |||||
| 201338 | ERK-2 (pT185) | 201338 | P28482 | pT185 |