Highly-multiplexed imaging by Cyclic Immunofluorescence (CycIF) of protein levels and protein phosphorylation states in the MCF 10A breast cell line treated with EGF or four kinase inhibitors - Dataset (ID:20267)
- Detail
- Small Molecules Studied
- Cell Lines Studied
- Proteins Studied
- Antibodies Studied
- Other Reagents Studied
- Results
Proteins Studied
Download: Excel (XLSX), Comma-separated (CSV)
| LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
|---|---|---|---|---|---|---|---|---|---|
| 200482 | Akt-1 | 200482 | P31749 | RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha | |||||
| 200483 | Akt-2 | 200483 | P31751 | RAC-beta serine/threonine-protein kinase; Protein kinase Akt-2; Protein kinase B beta; PKB beta; RAC-PK-beta | |||||
| 200484 | Akt-3 | 200484 | Q9Y243 | RAC-gamma serine/threonine-protein kinase; Protein kinase Akt-3; Protein kinase B gamma; PKB gamma; RAC-PK-gamma; STK-2 | |||||
| 201339 | Aurora kinase A (pT288) | 201339 | O14965 | pT288 | |||||
| 201340 | Aurora kinase B (pT232) | 201340 | Q96GD4 | pT232 | |||||
| 201341 | Aurora kinase C (pT198) | 201341 | Q9UQB9 | pT198 | |||||
| 201352 | BAX | 201352 | Q07812 | Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4 | |||||
| 201316 | Beta-actin | 201316 | P60709 | Actin, cytoplasmic 1 | |||||
| 201351 | Cyclin-D1 | 201351 | P24385 | G1/S-specific cyclin-D1; B-cell lymphoma 1 protein; BCL-1; BCL-1 oncogene; PRAD1 oncogene | |||||
| 201353 | E-cadherin | 201353 | P12830 | CAM 120/80; Epithelial cadherin; E-cadherin; Uvomorulin; CD324 | |||||
| 201357 | EGF | 201357 | P01133 | Epidermal Growth Factor; Urogastrone; URG | PeproTech | ||||
| 200507 | EGFR | 200507 | P00533 | Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1 | |||||
| 201337 | ERK-1 (pT202) | 201337 | P27361 | pT202 | |||||
| 201303 | ERK-1 (pT202; pY204) | 201303 | P27361 | pT202; pY204 | |||||
| 201338 | ERK-2 (pT185) | 201338 | P28482 | pT185 | |||||
| 201304 | ERK-2 (pT185; pY187) | 201304 | P28482 | pT185; pY187 | |||||
| 201350 | FOXO3a | 201350 | O43524 | Forkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1 | |||||
| 201314 | H2A.X (pS139) | 201314 | P16104 | pS139 | |||||
| 201294 | H3 (pS10) | 201294 | P68431 | pS10 | |||||
| 201311 | K10 | 201311 | P13645 | Keratin, type I cytoskeletal 10; Cytokeratin-10; CK-10 | |||||
| 201312 | K13 | 201312 | P13646 | Keratin, type I cytoskeletal 13; Cytokeratin-13; CK-13 | |||||
| 201313 | K18 | 201313 | P05783 | Keratin, type I cytoskeletal 18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18 | |||||
| 201305 | K4 | 201305 | P19013 | Keratin, type II cytoskeletal 4; Cytokeratin-4; CK-4; Keratin-4; Type-II keratin Kb4 | |||||
| 201306 | K5 | 201306 | P13647 | Keratin, type II cytoskeletal 5; 58 kDa cytokeratin; Cytokeratin-5; CK-5; Keratin-5; Type-II keratin Kb5 | |||||
| 201307 | K6A | 201307 | P02538 | Keratin, type II cytoskeletal 6A; Cytokeratin-6A; CK-6A; Cytokeratin-6D; CK-6D; Keratin-6A; Type-II keratin Kb6; Hom s 5 |