Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 2 of 3: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20257)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Erlotinib | 3.1623 | uM | 7 | 5000.00 | 1699.69 | 5495.33 | 5670.58 | 0.9689 | 0.9637 |
| SK-BR-3 | Linsitinib | 3.1623 | uM | 7 | 312.50 | 169.63 | 274.00 | 265.67 | 1.0349 | 1.1500 |
| MCF7 | Nilotinib | 3.1623 | uM | 10 | 1250.00 | 353.09 | 2355.00 | 2368.75 | 1.0161 | 1.0265 |
| BT-20 | Etoposide | 3.1623 | uM | 5 | 1250.00 | 675.75 | 971.00 | 2016.08 | 0.4829 | 0.2600 |
| SK-BR-3 | Palbociclib | 3.1623 | uM | 5 | 1250.00 | 731.83 | 1367.00 | 1811.21 | 0.7561 | 0.6157 |
| Hs 578T | Erlotinib | 3.1623 | uM | 10 | 1250.00 | 573.23 | 2841.33 | 3017.50 | 0.9418 | 0.9503 |
| SK-BR-3 | Lapatinib | 3.1623 | uM | 8 | 5000.00 | 1743.19 | 3943.33 | 6230.25 | 0.6329 | 0.5592 |
| SK-BR-3 | Linsitinib | 3.1623 | uM | 7 | 5000.00 | 1699.69 | 4841.00 | 5670.58 | 0.8537 | 0.8258 |
| MDA-MB-231 | Linsitinib | 3.1623 | uM | 10 | 1250.00 | 520.59 | 2628.00 | 2644.17 | 0.9924 | 0.9917 |
| SK-BR-3 | Omipalisib | 3.1623 | uM | 5 | 2500.00 | 1529.25 | 1482.67 | 3636.33 | 0.4077 | -0.0247 |
| BT-20 | Omipalisib | 3.1623 | uM | 3 | 625.00 | 278.42 | 109.33 | 689.17 | 0.1576 | -0.5230 |
| MCF 10A | Nilotinib | 3.1623 | uM | 5 | 156.25 | 36.94 | 1736.00 | 1928.50 | 0.9050 | 0.9633 |
| SK-BR-3 | Linsitinib | 3.1623 | uM | 8 | 5000.00 | 1743.19 | 5285.00 | 6230.25 | 0.8482 | 0.8284 |
| MCF 10A | NVP-TAE684 | 3.1623 | uM | 6 | 625.00 | 231.54 | 699.67 | 6394.33 | 0.1102 | 0.2583 |
| SK-BR-3 | Methotrexate | 3.1623 | uM | 5 | 2500.00 | 1529.25 | 2371.33 | 3636.33 | 0.6525 | 0.4210 |
| Hs 578T | Lapatinib | 3.1623 | uM | 10 | 1250.00 | 573.23 | 3120.33 | 3017.50 | 1.0345 | 1.0286 |
| MCF 10A | Palbociclib | 3.1623 | uM | 6 | 625.00 | 231.54 | 994.00 | 5885.83 | 0.1680 | 0.3603 |
| BT-20 | PLX-4720 | 3.1623 | uM | 3 | 312.50 | 136.54 | 364.33 | 294.17 | 1.2388 | 1.4279 |
| BT-20 | Methotrexate | 3.1623 | uM | 5 | 2500.00 | 1400.29 | 2472.33 | 4476.92 | 0.5522 | 0.4030 |
| Hs 578T | Palbociclib | 3.1623 | uM | 1 | 625.00 | 382.17 | 682.67 | 1678.83 | 0.4567 | 45813.4075 |
| BT-20 | Erlotinib | 3.1623 | uM | 7 | 2500.00 | 1312.79 | 3446.33 | 4280.58 | 0.8052 | 0.7613 |
| BT-20 | Erlotinib | 3.1623 | uM | 8 | 156.25 | 28.44 | 135.33 | 91.42 | 1.4740 | 1.5136 |