Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 1 of 3: Cell count and normalized growth rate inhibition values. - Dataset (ID:20256)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Taxol | 0.1 | uM | 6 | 156.25 | 23.44 | 62.00 | 702.50 | 0.0883 | 0.2193 |
| BT-20 | 0 | uM | 7 | 156.25 | 28.40 | 2.00 | 117.50 | 0.0170 | -0.7261 | |
| MCF 10A | Palbociclib | 0.031623 | uM | 6 | 156.25 | 23.44 | 826.00 | 702.50 | 1.1758 | 1.0671 |
| BT-20 | Erlotinib | 10 | uM | 7 | 156.25 | 28.40 | 137.00 | 117.50 | 1.1660 | 1.1556 |
| MCF 10A | Palbociclib | 19.9526 | uM | 6 | 156.25 | 23.44 | 94.00 | 702.50 | 0.1338 | 0.3273 |
| BT-20 | Erlotinib | 19.9526 | uM | 7 | 156.25 | 28.40 | 152.00 | 117.50 | 1.2936 | 1.2678 |
| MCF 10A | Omipalisib | 10 | uM | 6 | 156.25 | 23.44 | 51.00 | 702.50 | 0.0726 | 0.1717 |
| BT-20 | 17-AAG | 10 | uM | 7 | 156.25 | 28.40 | 57.00 | 117.50 | 0.4851 | 0.4051 |
| MCF 10A | 0 | uM | 6 | 156.25 | 23.44 | 727.00 | 702.50 | 1.0349 | 1.0140 | |
| BT-20 | 17-AAG | 0.0016596 | uM | 7 | 156.25 | 28.40 | 147.00 | 117.50 | 1.2511 | 1.2310 |
| SK-BR-3 | Methotrexate | 0.31623 | uM | 5 | 156.25 | 28.48 | 102.00 | 71.25 | 1.4316 | 1.6230 |
| BT-20 | 0 | uM | 7 | 156.25 | 28.40 | 2.00 | 117.50 | 0.0170 | -0.7261 | |
| SK-BR-3 | Nilotinib | 0.0033113 | uM | 5 | 156.25 | 28.48 | 81.00 | 89.00 | 0.9101 | 0.8886 |
| BT-20 | Erlotinib | 0.01 | uM | 8 | 156.25 | 28.44 | 107.00 | 100.00 | 1.0700 | 1.0760 |
| SK-BR-3 | 0 | uM | 5 | 156.25 | 28.48 | 74.00 | 89.00 | 0.8315 | 0.7876 | |
| BT-20 | 17-AAG | 0.1 | uM | 7 | 156.25 | 28.40 | 55.00 | 117.50 | 0.4681 | 0.3808 |
| SK-BR-3 | Nilotinib | 3.1623 | uM | 5 | 156.25 | 28.48 | 113.00 | 89.00 | 1.2697 | 1.3126 |
| BT-20 | Linsitinib | 19.9526 | uM | 7 | 156.25 | 28.40 | 56.00 | 117.50 | 0.4766 | 0.3930 |
| SK-BR-3 | Palbociclib | 0.0033113 | uM | 5 | 156.25 | 28.48 | 125.00 | 71.25 | 1.7544 | 2.0588 |
| BT-20 | 0 | uM | 7 | 156.25 | 28.40 | 2.00 | 117.50 | 0.0170 | -0.7261 | |
| MCF 10A | PLX-4720 | 10 | uM | 5 | 156.25 | 36.94 | 2480.00 | 2218.25 | 1.1180 | 1.0381 |
| BT-20 | 0 | uM | 7 | 156.25 | 28.40 | 101.00 | 117.50 | 0.8596 | 0.8576 | |
| SK-BR-3 | PLX-4720 | 0.0033113 | uM | 5 | 156.25 | 28.48 | 83.00 | 89.00 | 0.9326 | 0.9169 |
| BT-20 | Erlotinib | 0.31623 | uM | 7 | 156.25 | 28.40 | 145.00 | 117.50 | 1.2340 | 1.2162 |
| MCF 10A | 0 | uM | 6 | 156.25 | 23.44 | 674.00 | 702.50 | 0.9594 | 0.9832 |