Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 1 of 3: Cell count and normalized growth rate inhibition values. - Dataset (ID:20256)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | PLX-4720 | 3.1623 | uM | 5 | 625.00 | 399.25 | 8802.00 | 8841.75 | 0.9955 | 0.9980 |
| MCF 10A | NVP-TAE684 | 3.1623 | uM | 5 | 625.00 | 399.25 | 872.00 | 8841.75 | 0.0986 | 0.1910 |
| Hs 578T | NVP-TAE684 | 3.1623 | uM | 1 | 1250.00 | 718.46 | 647.00 | 2098.00 | 0.3084 | -0.0655 |
| BT-20 | Omipalisib | 3.1623 | uM | 4 | 2500.00 | 1354.79 | 472.00 | 4358.25 | 0.1083 | -0.4650 |
| Hs 578T | PLX-4720 | 3.1623 | uM | 1 | 1250.00 | 718.46 | 2435.00 | 2098.00 | 1.1606 | 1.2023 |
| MCF 10A | Nilotinib | 3.1623 | uM | 5 | 625.00 | 399.25 | 8399.00 | 8841.75 | 0.9499 | 0.9771 |
| BT-20 | Erlotinib | 3.1623 | uM | 9 | 625.00 | 320.09 | 681.00 | 736.00 | 0.9253 | 0.8748 |
| MCF7 | Methotrexate | 3.1623 | uM | 1 | 625.00 | 173.50 | 266.00 | 261.25 | 1.0182 | 1.0620 |
| BT-20 | Palbociclib | 3.1623 | uM | 4 | 2500.00 | 1354.79 | 1491.00 | 4358.25 | 0.3421 | 0.0585 |
| MCF 10A | NVP-TAE684 | 3.1623 | uM | 5 | 1250.00 | 996.83 | 3088.00 | 10779.25 | 0.2865 | 0.3898 |
| MDA-MB-231 | PLX-4720 | 3.1623 | uM | 2 | 5000.00 | 2676.73 | 5380.00 | 5442.25 | 0.9886 | 0.9777 |
| BT-20 | NVP-TAE684 | 3.1623 | uM | 3 | 2500.00 | 1321.92 | 1469.00 | 3814.75 | 0.3851 | 0.0714 |
| Hs 578T | Etoposide | 3.1623 | uM | 1 | 1250.00 | 718.46 | 797.00 | 2098.00 | 0.3799 | 0.0694 |
| MCF 10A | Palbociclib | 3.1623 | uM | 2 | 625.00 | 277.50 | 410.00 | 3531.75 | 0.1161 | 0.1122 |
| Hs 578T | Palbociclib | 3.1623 | uM | 1 | 312.50 | 222.17 | 229.00 | 474.50 | 0.4826 | 0.0281 |
| BT-20 | PLX-4720 | 3.1623 | uM | 3 | 2500.00 | 1321.92 | 4053.00 | 3814.75 | 1.0625 | 1.0808 |
| MCF 10A | Etoposide | 3.1623 | uM | 5 | 2500.00 | 2253.88 | 1776.00 | 10199.25 | 0.1741 | -0.1036 |
| MCF 10A | NVP-TAE684 | 3.1623 | uM | 2 | 5000.00 | 3410.67 | 2774.00 | 7047.75 | 0.3936 | -0.1791 |
| BT-20 | Omipalisib | 3.1623 | uM | 4 | 5000.00 | 2571.29 | 612.00 | 7465.25 | 0.0820 | -0.6068 |
| MCF 10A | Nilotinib | 3.1623 | uM | 5 | 2500.00 | 2253.88 | 10079.00 | 10199.25 | 0.9882 | 0.9891 |
| MDA-MB-231 | NVP-TAE684 | 3.1623 | uM | 2 | 5000.00 | 2676.73 | 2368.00 | 5442.25 | 0.4351 | -0.1128 |
| BT-20 | Palbociclib | 3.1623 | uM | 4 | 5000.00 | 2571.29 | 3261.00 | 7465.25 | 0.4368 | 0.1671 |
| Hs 578T | Nilotinib | 3.1623 | uM | 1 | 1250.00 | 718.46 | 2071.00 | 2098.00 | 0.9871 | 0.9833 |
| MCF7 | Nilotinib | 3.1623 | uM | 11 | 312.50 | 95.00 | 856.00 | 993.75 | 0.8614 | 0.9138 |
| MCF7 | Palbociclib | 3.1623 | uM | 11 | 312.50 | 95.00 | 392.00 | 993.75 | 0.3945 | 0.5197 |