PF-3758309 KiNativ -- single dose experiment - Dataset (ID:20254)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| PF-3758309 | THP-1 | NEK1 | DIKSQNIFLTK | Lys2 | 7.3 | 1 | uM |
| PF-3758309 | THP-1 | NEK3 | SKNIFLTQNGK | Activation Loop | -1.7 | 1 | uM |
| PF-3758309 | THP-1 | NEK6,NEK7 | DIKPANVFITATGVVK | Lys2 | -4.4 | 1 | uM |
| PF-3758309 | THP-1 | NEK7 | AACLLDGVPVALKK | Lys1 | -13.2 | 1 | uM |
| PF-3758309 | THP-1 | NEK9 | TEDDSLVVWKEVDLTR | Lys1 | 21.4 | 1 | uM |
| PF-3758309 | THP-1 | NEK9 | DIKTLNIFLTK | Lys2 | 36.6 | 1 | uM |
| PF-3758309 | THP-1 | p38a | DLKPSNLAVNEDCELK | Lys2 | 1.1 | 1 | uM |
| PF-3758309 | THP-1 | MK14 | QELNKTIWEVPER | Protein Kinase Domain | 7.4 | 1 | uM |
| PF-3758309 | THP-1 | p38d,p38g | DLKPGNLAVNEDCELK | Lys2 | 5.2 | 1 | uM |
| PF-3758309 | THP-1 | KS6B1 | DLKPENIMLNHQGHVK | Lys2 | -8.0 | 1 | uM |
| PF-3758309 | THP-1 | CDK16 | LTDNLVALKEIR | Lys1 | 65.8 | 1 | uM |
| PF-3758309 | THP-1 | CDK16 | DLKPQNLLINER | Lys2 | 63.7 | 1 | uM |
| PF-3758309 | THP-1 | PCTAIRE2 | DLKPQNLLINEK | Lys2 | 70.0 | 1 | uM |
| PF-3758309 | THP-1 | PCTAIRE2,PCTAIRE3 | SKLTENLVALKEIR | Lys1 | 73.1 | 1 | uM |
| PF-3758309 | THP-1 | PDK1 | EYAIKILEK | Lys1 | 55.6 | 1 | uM |
| PF-3758309 | THP-1 | CDK14 | LVALKVIR | Lys1 | 57.8 | 1 | uM |
| PF-3758309 | THP-1 | PIK3CB | VFGEDSVGVIFKNGDDLR | ATP | 7.1 | 1 | uM |
| PF-3758309 | THP-1 | PIK3CD | VNWLAHNVSKDNRQ | ATP | -0.4 | 1 | uM |
| PF-3758309 | THP-1 | PIK3CG | KKPLWLEFK | ATP | 2.3 | 1 | uM |
| PF-3758309 | THP-1 | PI42C | TLVIKEVSSEDIADMHSNLSNYHQYIVK | ATP | -20.7 | 1 | uM |
| PF-3758309 | THP-1 | FYV1 | GGKSGAAFYATEDDRFILK | ATP | -0.9 | 1 | uM |
| PF-3758309 | THP-1 | PKD2 | DVAVKVIDK | Lys1 | 72.5 | 1 | uM |
| PF-3758309 | THP-1 | PKN1 | VLLSEFRPSGELFAIKALK | Lys1 | 68.6 | 1 | uM |
| PF-3758309 | THP-1 | PKR | DLKPSNIFLVDTK | Lys2 | 2.3 | 1 | uM |
| PF-3758309 | THP-1 | PLK1 | CFEISDADTKEVFAGKIVPK | Lys1 | 2.5 | 1 | uM |