LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | AZD8055 | 0.37 | uM | LJP6 | 0.4031 | 0.0108 | 0.2453 | 0.0025 |
| MDA-MB-231 | AZD8055 | 1.11 | uM | LJP6 | 0.3890 | 0.0061 | 0.2237 | 0.0089 |
| MDA-MB-231 | AZD8055 | 3.33 | uM | LJP6 | 0.3443 | 0.0242 | 0.1458 | 0.0573 |
| MDA-MB-231 | AZD8055 | 10 | uM | LJP6 | 0.2400 | 0.0576 | -0.0657 | 0.1439 |
| MDA-MB-231 | Sorafenib | 0.04 | uM | LJP6 | 1.0133 | 0.0246 | 1.0148 | 0.0258 |
| MDA-MB-231 | Sorafenib | 0.12 | uM | LJP6 | 0.9213 | 0.0721 | 0.9172 | 0.0751 |
| MDA-MB-231 | Sorafenib | 0.37 | uM | LJP6 | 0.9298 | 0.0626 | 0.9266 | 0.0647 |
| MDA-MB-231 | Sorafenib | 1.11 | uM | LJP6 | 0.9414 | 0.0997 | 0.9377 | 0.1054 |
| MDA-MB-231 | Sorafenib | 3.33 | uM | LJP6 | 0.9215 | 0.0739 | 0.9176 | 0.0771 |
| MDA-MB-231 | Sorafenib | 10 | uM | LJP6 | 0.8175 | 0.0652 | 0.8008 | 0.0692 |
| MDA-MB-231 | CP466722 | 0.04 | uM | LJP5 | 1.0550 | 0.0333 | 1.0547 | 0.0326 |
| MDA-MB-231 | CP466722 | 0.12 | uM | LJP5 | 1.0167 | 0.0329 | 1.0156 | 0.0334 |
| MDA-MB-231 | CP466722 | 0.37 | uM | LJP5 | 0.8937 | 0.1194 | 0.7849 | 0.2280 |
| MDA-MB-231 | CP466722 | 1.11 | uM | LJP5 | 0.9410 | 0.0220 | 0.9376 | 0.0238 |
| MDA-MB-231 | CP466722 | 3.33 | uM | LJP5 | 0.9108 | 0.0528 | 0.9035 | 0.0579 |
| MDA-MB-231 | CP466722 | 10 | uM | LJP5 | 0.6073 | 0.1132 | 0.5344 | 0.1442 |
| MDA-MB-231 | CP724714 | 0.04 | uM | LJP5 | 0.9057 | 0.0714 | 0.8991 | 0.0771 |
| MDA-MB-231 | CP724714 | 0.12 | uM | LJP5 | 0.9031 | 0.0697 | 0.8961 | 0.0758 |
| MDA-MB-231 | CP724714 | 0.37 | uM | LJP5 | 0.9041 | 0.0657 | 0.8974 | 0.0712 |
| MDA-MB-231 | CP724714 | 1.11 | uM | LJP5 | 0.9164 | 0.0475 | 0.9121 | 0.0506 |
| MDA-MB-231 | CP724714 | 3.33 | uM | LJP5 | 0.8468 | 0.0773 | 0.8322 | 0.0880 |
| MDA-MB-231 | CP724714 | 10 | uM | LJP5 | 0.8281 | 0.0740 | 0.8124 | 0.0838 |
| MDA-MB-231 | Alvocidib | 0.04 | uM | LJP6 | 0.3742 | 0.0825 | 0.1836 | 0.1448 |
| MDA-MB-231 | Alvocidib | 0.12 | uM | LJP6 | 0.1573 | 0.0200 | -0.2388 | 0.0716 |
| MDA-MB-231 | Alvocidib | 0.37 | uM | LJP6 | 0.1444 | 0.0194 | -0.2729 | 0.0742 |