LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Withaferin A | 1.11 | uM | LJP6 | 0.3352 | 0.0137 | -0.1347 | 0.0497 |
| SK-BR-3 | Withaferin A | 3.33 | uM | LJP5 | 0.2520 | 0.0320 | -0.2739 | 0.0372 |
| SK-BR-3 | Withaferin A | 3.33 | uM | LJP6 | 0.2419 | 0.0093 | -0.3256 | 0.0646 |
| SK-BR-3 | Withaferin A | 10 | uM | LJP5 | 0.2435 | 0.0029 | -0.2898 | 0.0646 |
| SK-BR-3 | Withaferin A | 10 | uM | LJP6 | 0.2706 | 0.0036 | -0.2657 | 0.0850 |
| MDA-MB-231 | Seliciclib | 0.04 | uM | LJP5 | 1.0285 | 0.0199 | 1.0281 | 0.0201 |
| MDA-MB-231 | Seliciclib | 0.12 | uM | LJP5 | 0.9733 | 0.0161 | 0.9714 | 0.0174 |
| MDA-MB-231 | Seliciclib | 0.37 | uM | LJP5 | 0.9296 | 0.0166 | 0.9262 | 0.0171 |
| MDA-MB-231 | Seliciclib | 1.11 | uM | LJP5 | 0.8870 | 0.0180 | 0.8799 | 0.0192 |
| MDA-MB-231 | Seliciclib | 3.33 | uM | LJP5 | 0.8258 | 0.0397 | 0.8114 | 0.0442 |
| MDA-MB-231 | Seliciclib | 10 | uM | LJP5 | 0.5010 | 0.0291 | 0.4008 | 0.0392 |
| MDA-MB-231 | AT-7519 | 0.04 | uM | LJP6 | 0.7679 | 0.0853 | 0.7323 | 0.1103 |
| MDA-MB-231 | AT-7519 | 0.12 | uM | LJP6 | 0.4539 | 0.1223 | 0.2909 | 0.2189 |
| MDA-MB-231 | AT-7519 | 0.37 | uM | LJP6 | 0.1899 | 0.0461 | -0.1706 | 0.1289 |
| MDA-MB-231 | AT-7519 | 1.11 | uM | LJP6 | 0.1423 | 0.0377 | -0.2907 | 0.1272 |
| MDA-MB-231 | AT-7519 | 3.33 | uM | LJP6 | 0.1178 | 0.0296 | -0.3554 | 0.1129 |
| MDA-MB-231 | AT-7519 | 10 | uM | LJP6 | 0.1067 | 0.0280 | -0.3883 | 0.1102 |
| MDA-MB-231 | AZD7762 | 0.04 | uM | LJP6 | 0.7354 | 0.0947 | 0.7000 | 0.1083 |
| MDA-MB-231 | AZD7762 | 0.12 | uM | LJP6 | 0.4959 | 0.0417 | 0.3866 | 0.0600 |
| MDA-MB-231 | AZD7762 | 0.37 | uM | LJP6 | 0.3786 | 0.0663 | 0.1957 | 0.1226 |
| MDA-MB-231 | AZD7762 | 1.11 | uM | LJP6 | 0.2185 | 0.0268 | -0.0971 | 0.0773 |
| MDA-MB-231 | AZD7762 | 3.33 | uM | LJP6 | 0.1548 | 0.0229 | -0.2464 | 0.0809 |
| MDA-MB-231 | AZD7762 | 10 | uM | LJP6 | 0.1387 | 0.0250 | -0.2902 | 0.0901 |
| MDA-MB-231 | AZD8055 | 0.04 | uM | LJP6 | 0.5644 | 0.0280 | 0.4840 | 0.0267 |
| MDA-MB-231 | AZD8055 | 0.12 | uM | LJP6 | 0.4497 | 0.0283 | 0.3175 | 0.0275 |