LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|
SK-BR-3 | NVP-AEW541 | 3.33 | uM | LJP5 | 0.9766 | 0.0373 | 0.9712 | 0.0483 |
SK-BR-3 | NVP-AEW541 | 10 | uM | LJP5 | 0.5265 | 0.0719 | 0.2442 | 0.1307 |
SK-BR-3 | PHA-665752 | 0.04 | uM | LJP5 | 1.0228 | 0.0294 | 1.0367 | 0.0412 |
SK-BR-3 | PHA-665752 | 0.12 | uM | LJP5 | 1.0420 | 0.0209 | 1.0606 | 0.0303 |
SK-BR-3 | PHA-665752 | 0.37 | uM | LJP5 | 1.0454 | 0.0357 | 1.0701 | 0.0503 |
SK-BR-3 | PHA-665752 | 1.11 | uM | LJP5 | 1.0443 | 0.0378 | 1.0604 | 0.0564 |
SK-BR-3 | PHA-665752 | 3.33 | uM | LJP5 | 0.9664 | 0.0215 | 0.9555 | 0.0271 |
SK-BR-3 | PHA-665752 | 10 | uM | LJP5 | 0.4046 | 0.1786 | 0.0120 | 0.2871 |
SK-BR-3 | PI103 | 0.04 | uM | LJP6 | 0.9316 | 0.0231 | 0.8996 | 0.0258 |
SK-BR-3 | PI103 | 0.12 | uM | LJP6 | 0.7288 | 0.0588 | 0.5787 | 0.0580 |
SK-BR-3 | PI103 | 0.37 | uM | LJP6 | 0.5232 | 0.0524 | 0.2212 | 0.0302 |
SK-BR-3 | PI103 | 1.11 | uM | LJP6 | 0.4015 | 0.0316 | -0.0082 | 0.0868 |
SK-BR-3 | PI103 | 3.33 | uM | LJP6 | 0.3641 | 0.0325 | -0.0811 | 0.1154 |
SK-BR-3 | PI103 | 10 | uM | LJP6 | 0.3349 | 0.0244 | -0.1365 | 0.1011 |
SK-BR-3 | Dovitinib | 0.04 | uM | LJP5 | 0.8124 | 0.0361 | 0.7115 | 0.0664 |
SK-BR-3 | Dovitinib | 0.12 | uM | LJP5 | 0.7769 | 0.0152 | 0.6587 | 0.0383 |
SK-BR-3 | Dovitinib | 0.37 | uM | LJP5 | 0.6706 | 0.0444 | 0.4969 | 0.0358 |
SK-BR-3 | Dovitinib | 1.11 | uM | LJP5 | 0.6563 | 0.0524 | 0.4738 | 0.0468 |
SK-BR-3 | Dovitinib | 3.33 | uM | LJP5 | 0.5403 | 0.0327 | 0.2754 | 0.0230 |
SK-BR-3 | Dovitinib | 10 | uM | LJP5 | 0.4660 | 0.0189 | 0.1421 | 0.0262 |
SK-BR-3 | GSK 690693 | 0.04 | uM | LJP5 | 0.7250 | 0.0173 | 0.5784 | 0.0370 |
SK-BR-3 | GSK 690693 | 0.12 | uM | LJP5 | 0.7092 | 0.0209 | 0.5551 | 0.0199 |
SK-BR-3 | GSK 690693 | 0.37 | uM | LJP5 | 0.7100 | 0.0164 | 0.5563 | 0.0218 |
SK-BR-3 | GSK 690693 | 1.11 | uM | LJP5 | 0.7193 | 0.0153 | 0.5711 | 0.0224 |
SK-BR-3 | GSK 690693 | 3.33 | uM | LJP5 | 0.7501 | 0.0122 | 0.6199 | 0.0182 |