LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Normalized Growth Rate Inhibition Value Standard Error of the Mean for Normalized Growth Rate Inhibition Value
SK-BR-3 NVP-AEW541
3.33
uM
LJP5
0.9766 0.0373 0.9712 0.0483
SK-BR-3 NVP-AEW541
10
uM
LJP5
0.5265 0.0719 0.2442 0.1307
SK-BR-3 PHA-665752
0.04
uM
LJP5
1.0228 0.0294 1.0367 0.0412
SK-BR-3 PHA-665752
0.12
uM
LJP5
1.0420 0.0209 1.0606 0.0303
SK-BR-3 PHA-665752
0.37
uM
LJP5
1.0454 0.0357 1.0701 0.0503
SK-BR-3 PHA-665752
1.11
uM
LJP5
1.0443 0.0378 1.0604 0.0564
SK-BR-3 PHA-665752
3.33
uM
LJP5
0.9664 0.0215 0.9555 0.0271
SK-BR-3 PHA-665752
10
uM
LJP5
0.4046 0.1786 0.0120 0.2871
SK-BR-3 PI103
0.04
uM
LJP6
0.9316 0.0231 0.8996 0.0258
SK-BR-3 PI103
0.12
uM
LJP6
0.7288 0.0588 0.5787 0.0580
SK-BR-3 PI103
0.37
uM
LJP6
0.5232 0.0524 0.2212 0.0302
SK-BR-3 PI103
1.11
uM
LJP6
0.4015 0.0316 -0.0082 0.0868
SK-BR-3 PI103
3.33
uM
LJP6
0.3641 0.0325 -0.0811 0.1154
SK-BR-3 PI103
10
uM
LJP6
0.3349 0.0244 -0.1365 0.1011
SK-BR-3 Dovitinib
0.04
uM
LJP5
0.8124 0.0361 0.7115 0.0664
SK-BR-3 Dovitinib
0.12
uM
LJP5
0.7769 0.0152 0.6587 0.0383
SK-BR-3 Dovitinib
0.37
uM
LJP5
0.6706 0.0444 0.4969 0.0358
SK-BR-3 Dovitinib
1.11
uM
LJP5
0.6563 0.0524 0.4738 0.0468
SK-BR-3 Dovitinib
3.33
uM
LJP5
0.5403 0.0327 0.2754 0.0230
SK-BR-3 Dovitinib
10
uM
LJP5
0.4660 0.0189 0.1421 0.0262
SK-BR-3 GSK 690693
0.04
uM
LJP5
0.7250 0.0173 0.5784 0.0370
SK-BR-3 GSK 690693
0.12
uM
LJP5
0.7092 0.0209 0.5551 0.0199
SK-BR-3 GSK 690693
0.37
uM
LJP5
0.7100 0.0164 0.5563 0.0218
SK-BR-3 GSK 690693
1.11
uM
LJP5
0.7193 0.0153 0.5711 0.0224
SK-BR-3 GSK 690693
3.33
uM
LJP5
0.7501 0.0122 0.6199 0.0182