LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 Mitoxantrone
3.33
uM
LJP6
 72
hr
 1235 205 4405 0.0467 -0.6246
Hs 578T Torin1
10
uM
LJP6
 72
hr
 658 459 3761 0.1222 -0.1334
MDA-MB-231 Mitoxantrone
10
uM
LJP6
 72
hr
 1235 108 4405 0.0247 -0.7348
MCF 10A Afatinib
0.04
uM
LJP6
 72
hr
 962 1713 10692 0.1603 0.1807
MDA-MB-231 Radicicol
0.04
uM
LJP6
 72
hr
 1235 4715 4405 1.0714 1.0773
MCF 10A CGP60474
0.04
uM
LJP6
 72
hr
 962 400 10692 0.0375 -0.2234
MDA-MB-231 Radicicol
0.12
uM
LJP6
 72
hr
 1235 3118 4405 0.7088 0.6577
MCF 10A PD0325901
0.04
uM
LJP6
 72
hr
 962 2212 10692 0.2070 0.2700
MDA-MB-231 Radicicol
0.37
uM
LJP6
 72
hr
 1235 1539 4405 0.3504 0.1274
MCF 10A CGP60474
0.12
uM
LJP6
 72
hr
 962 253 10692 0.0237 -0.3195
MDA-MB-231 Radicicol
1.11
uM
LJP6
 72
hr
 1235 1180 4405 0.2688 -0.0255
MCF 10A Afatinib
0.12
uM
LJP6
 72
hr
 962 1521 10692 0.1423 0.1408
MDA-MB-231 Radicicol
3.33
uM
LJP6
 72
hr
 1235 1072 4405 0.2440 -0.0746
MCF 10A CGP60474
0.37
uM
LJP6
 72
hr
 962 277 10692 0.0260 -0.3019
MDA-MB-231 Radicicol
10
uM
LJP6
 72
hr
 1235 833 4405 0.1887 -0.1957