LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 TGX221
0.12
uM
LJP5
 72
hr
 1235 4117 4660 0.8825 0.8725
MDA-MB-231 TGX221
0.37
uM
LJP5
 72
hr
 1235 4099 4660 0.8785 0.8680
MDA-MB-231 TGX221
1.11
uM
LJP5
 72
hr
 1235 4311 4660 0.9228 0.9154
MDA-MB-231 TGX221
3.33
uM
LJP5
 72
hr
 1235 4251 4660 0.9106 0.9025
MDA-MB-231 TGX221
10
uM
LJP5
 72
hr
 1235 4077 4660 0.8742 0.8637
MDA-MB-231 GSK1059615
0.04
uM
LJP5
 72
hr
 1235 4766 4660 1.0222 1.0228
MDA-MB-231 GSK1059615
0.04
uM
LJP6
 72
hr
 1235 3977 4405 0.9005 0.8836
MDA-MB-231 GSK1059615
0.12
uM
LJP5
 72
hr
 1235 4527 4660 0.9732 0.9724
MDA-MB-231 GSK1059615
0.12
uM
LJP6
 72
hr
 1235 4126 4405 0.9358 0.9277
MDA-MB-231 GSK1059615
0.37
uM
LJP5
 72
hr
 1235 4112 4660 0.8817 0.8719
MDA-MB-231 GSK1059615
0.37
uM
LJP6
 72
hr
 1235 3933 4405 0.8920 0.8769
MDA-MB-231 GSK1059615
1.11
uM
LJP5
 72
hr
 1235 2452 4660 0.5251 0.4258
MDA-MB-231 GSK1059615
1.11
uM
LJP6
 72
hr
 1235 2124 4405 0.4780 0.3129
MDA-MB-231 GSK1059615
3.33
uM
LJP5
 72
hr
 1235 1118 4660 0.2400 -0.0524
MDA-MB-231 GSK1059615
3.33
uM
LJP6
 72
hr
 1235 1188 4405 0.2667 -0.0500
MDA-MB-231 GSK1059615
10
uM
LJP5
 72
hr
 1235 518 4660 0.1105 -0.3706
MDA-MB-231 GSK1059615
10
uM
LJP6
 72
hr
 1235 846 4405 0.1901 -0.2070
MDA-MB-231 Brivanib
0.04
uM
LJP5
 72
hr
 1235 4067 4660 0.8708 0.8583
MDA-MB-231 Brivanib
0.12
uM
LJP5
 72
hr
 1235 4196 4660 0.8994 0.8910
MDA-MB-231 Brivanib
0.37
uM
LJP5
 72
hr
 1235 4187 4660 0.8962 0.8861
MDA-MB-231 Brivanib
1.11
uM
LJP5
 72
hr
 1235 4270 4660 0.9136 0.9042
MDA-MB-231 Brivanib
3.33
uM
LJP5
 72
hr
 1235 4181 4660 0.8965 0.8883
MDA-MB-231 Brivanib
10
uM
LJP5
 72
hr
 1235 3080 4660 0.6610 0.6104
MDA-MB-231 CHIR-99021
0.04
uM
LJP6
 72
hr
 1235 3927 4405 0.8913 0.8782
MDA-MB-231 CHIR-99021
0.12
uM
LJP6
 72
hr
 1235 3769 4405 0.8550 0.8354