LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 CGP60474
1.11
uM
LJP6
 72
hr
 1097 538 3673 0.1464 -0.3367
BT-20 AZD 5438
10
uM
LJP6
 72
hr
 1097 540 3673 0.1470 -0.3343
BT-20 AT-7519
3.33
uM
LJP6
 72
hr
 1097 540 3673 0.1468 -0.3382
Hs 578T Dasatinib
3.33
uM
LJP6
 72
hr
 658 540 3761 0.1437 -0.0755
MDA-MB-231 Geldanamycin
10
uM
LJP5
 72
hr
 1235 541 4660 0.1163 -0.3517
MDA-MB-231 JNK-9L
10
uM
LJP6
 72
hr
 1235 541 4405 0.1230 -0.3626
Hs 578T SNS-032
0.12
uM
LJP6
 72
hr
 658 542 3761 0.1444 -0.0741
Hs 578T SNS-032
1.11
uM
LJP6
 72
hr
 658 548 3761 0.1457 -0.0704
MDA-MB-231 WZ-4-145
10
uM
LJP6
 72
hr
 1235 552 4405 0.1252 -0.3563
MCF 10A Mitoxantrone
10
uM
LJP6
 72
hr
 962 552 10692 0.0517 -0.1484
MDA-MB-231 SNS-032
0.12
uM
LJP6
 72
hr
 1235 554 4405 0.1259 -0.3546
Hs 578T Torin2
1.11
uM
LJP5
 72
hr
 658 554 3933 0.1408 -0.0671
Hs 578T Dasatinib
3.33
uM
LJP5
 72
hr
 658 556 3933 0.1414 -0.0638
SK-BR-3 LDN-193189
10
uM
LJP5
 72
hr
 1401 557 4245 0.1286 -0.4568
Hs 578T Momelotinib
10
uM
LJP5
 72
hr
 658 561 3933 0.1426 -0.0610
MDA-MB-231 AZD8055
10
uM
LJP6
 72
hr
 1235 562 4405 0.1271 -0.3529
Hs 578T AZD 5438
1.11
uM
LJP6
 72
hr
 658 562 3761 0.1496 -0.0609
MCF7 CGP60474
0.37
uM
LJP5
 72
hr
 1209 566 4203 0.1350 -0.3455
Hs 578T PF477736
3.33
uM
LJP5
 72
hr
 658 566 3933 0.1440 -0.0571
BT-20 Withaferin A
10
uM
LJP6
 72
hr
 1097 566 3673 0.1542 -0.3158
Hs 578T Y39983
10
uM
LJP6
 72
hr
 658 567 3761 0.1510 -0.0578
Hs 578T Dasatinib
1.11
uM
LJP5
 72
hr
 658 567 3933 0.1442 -0.0560
MCF7 CGP60474
10
uM
LJP5
 72
hr
 1209 568 4203 0.1357 -0.3435
Hs 578T PF562271
10
uM
LJP6
 72
hr
 658 568 3761 0.1511 -0.0577
Hs 578T Neratinib
10
uM
LJP5
 72
hr
 658 568 3933 0.1445 -0.0559