LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 Enzastaurin
10
uM
LJP5
 72
hr
 1097 4311 3846 1.1195 1.1266
SK-BR-3 WH-4-025
0.04
uM
LJP5
 72
hr
 1401 4737 4245 1.1201 1.1513
SK-BR-3 Linifanib
0.37
uM
LJP6
 72
hr
 1401 4681 4168 1.1232 1.1535
SK-BR-3 Nilotinib
0.37
uM
LJP5
 72
hr
 1401 4822 4245 1.1351 1.1650
SK-BR-3 YM 201636
0.04
uM
LJP5
 72
hr
 1401 4814 4245 1.1359 1.1686
SK-BR-3 SB590885
0.04
uM
LJP5
 72
hr
 1401 4804 4245 1.1362 1.1710
SK-BR-3 Nilotinib
1.11
uM
LJP5
 72
hr
 1401 4831 4245 1.1381 1.1695
SK-BR-3 XL147
0.12
uM
LJP5
 72
hr
 1401 4821 4245 1.1409 1.1763
SK-BR-3 XL147
3.33
uM
LJP5
 72
hr
 1401 4818 4245 1.1412 1.1776
SK-BR-3 TWS119
0.04
uM
LJP5
 72
hr
 1401 4829 4245 1.1428 1.1791
SK-BR-3 CP466722
0.04
uM
LJP5
 72
hr
 1401 4863 4245 1.1519 1.1903
MDA-MB-231 Celastrol
0.04
uM
LJP6
 72
hr
 1235 5069 4405 1.1523 1.1611
MDA-MB-231 PD173074
0.37
uM
LJP6
 72
hr
 1235 5078 4405 1.1552 1.1644
SK-BR-3 XL147
1.11
uM
LJP5
 72
hr
 1401 4944 4245 1.1686 1.2092
SK-BR-3 LDN-193189
0.04
uM
LJP5
 72
hr
 1401 4952 4245 1.1690 1.2085