LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 AZD7762
3.33
uM
LJP6
 72
hr
 1235 497 4405 0.1131 -0.3916
Hs 578T Torin2
10
uM
LJP5
 72
hr
 658 447 3933 0.1139 -0.1402
MDA-MB-231 Torin2
10
uM
LJP5
 72
hr
 1235 534 4660 0.1141 -0.3578
Hs 578T Pelitinib
10
uM
LJP5
 72
hr
 658 448 3933 0.1141 -0.1393
Hs 578T PF477736
10
uM
LJP5
 72
hr
 658 449 3933 0.1143 -0.1376
MCF 10A PHA-793887
0.37
uM
LJP6
 72
hr
 962 1224 10692 0.1145 0.0715
MDA-MB-231 CGP60474
0.12
uM
LJP6
 72
hr
 1235 506 4405 0.1147 -0.3866
MCF7 JNK-9L
1.11
uM
LJP6
 72
hr
 1209 460 4012 0.1147 -0.4285
MCF 10A Afatinib
10
uM
LJP6
 72
hr
 962 1227 10692 0.1148 0.0724
MCF 10A Geldanamycin
0.04
uM
LJP6
 72
hr
 962 1229 10692 0.1150 0.0729
Hs 578T WZ3105
10
uM
LJP5
 72
hr
 658 454 3933 0.1154 -0.1342
Hs 578T WZ3105
0.04
uM
LJP5
 72
hr
 658 454 3933 0.1154 -0.1352
Hs 578T Dasatinib
10
uM
LJP6
 72
hr
 658 436 3761 0.1159 -0.1512
Hs 578T CGP60474
0.37
uM
LJP5
 72
hr
 658 456 3933 0.1159 -0.1327
Hs 578T Omipalisib
3.33
uM
LJP6
 72
hr
 658 436 3761 0.1161 -0.1514
MDA-MB-231 Geldanamycin
10
uM
LJP5
 72
hr
 1235 541 4660 0.1163 -0.3517
BT-20 Omipalisib
10
uM
LJP6
 72
hr
 1097 428 3673 0.1164 -0.4180
BT-20 CGP60474
10
uM
LJP6
 72
hr
 1097 427 3673 0.1165 -0.4176
SK-BR-3 AT-7519
10
uM
LJP6
 72
hr
 1401 486 4168 0.1167 -0.4930
Hs 578T CGP60474
3.33
uM
LJP6
 72
hr
 658 440 3761 0.1170 -0.1480
Hs 578T WH-4-025
3.33
uM
LJP5
 72
hr
 658 460 3933 0.1170 -0.1307
MCF 10A PF562271
3.33
uM
LJP6
 72
hr
 962 1254 10692 0.1173 0.0785
MDA-MB-231 Alvocidib
0.12
uM
LJP6
 72
hr
 1235 517 4405 0.1174 -0.3787
Hs 578T AT-7519
1.11
uM
LJP6
 72
hr
 658 442 3761 0.1175 -0.1466
MCF 10A Torin1
10
uM
LJP6
 72
hr
 962 1262 10692 0.1180 0.0810