LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 SB590885
10
uM
LJP5
 72
hr
 1209 409 4203 0.0977 -0.4537
MDA-MB-231 Fedratinib
10
uM
LJP5
 72
hr
 1235 398 4660 0.0849 -0.4514
MDA-MB-231 Alvocidib
10
uM
LJP6
 72
hr
 1235 414 4405 0.0943 -0.4498
MDA-MB-231 A443654
3.33
uM
LJP6
 72
hr
 1235 414 4405 0.0940 -0.4497
Hs 578T Mitoxantrone
3.33
uM
LJP6
 72
hr
 658 147 3761 0.0393 -0.4481
MDA-MB-231 Dasatinib
10
uM
LJP6
 72
hr
 1235 436 4405 0.0982 -0.4446
MCF7 AT-7519
10
uM
LJP6
 72
hr
 1209 443 4012 0.1106 -0.4408
MDA-MB-231 CGP60474
1.11
uM
LJP5
 72
hr
 1235 407 4660 0.0875 -0.4405
MDA-MB-231 Alvocidib
1.11
uM
LJP6
 72
hr
 1235 432 4405 0.0979 -0.4377
MCF 10A LDN-193189
10
uM
LJP5
 72
hr
 962 136 10512 0.0130 -0.4374
MCF7 YM 201636
10
uM
LJP5
 72
hr
 1209 435 4203 0.1038 -0.4341
MDA-MB-231 WH-4-025
10
uM
LJP5
 72
hr
 1235 420 4660 0.0906 -0.4310
Hs 578T Mitoxantrone
3.33
uM
LJP5
 72
hr
 658 154 3933 0.0392 -0.4301
MCF7 JNK-9L
1.11
uM
LJP6
 72
hr
 1209 460 4012 0.1147 -0.4285
MDA-MB-231 Alvocidib
3.33
uM
LJP6
 72
hr
 1235 447 4405 0.1017 -0.4260
MDA-MB-231 PF431396
10
uM
LJP5
 72
hr
 1235 433 4660 0.0931 -0.4225
MDA-MB-231 Mitoxantrone
1.11
uM
LJP6
 72
hr
 1235 456 4405 0.1038 -0.4198
MDA-MB-231 CGP60474
0.37
uM
LJP6
 72
hr
 1235 459 4405 0.1041 -0.4182
BT-20 Omipalisib
10
uM
LJP6
 72
hr
 1097 428 3673 0.1164 -0.4180
MCF7 CGP60474
10
uM
LJP6
 72
hr
 1209 474 4012 0.1186 -0.4179
BT-20 CGP60474
10
uM
LJP6
 72
hr
 1097 427 3673 0.1165 -0.4176
MDA-MB-231 PF562271
10
uM
LJP6
 72
hr
 1235 460 4405 0.1045 -0.4169
MDA-MB-231 WZ3105
1.11
uM
LJP5
 72
hr
 1235 446 4660 0.0961 -0.4133
MDA-MB-231 Alvocidib
0.37
uM
LJP6
 72
hr
 1235 470 4405 0.1069 -0.4121
MDA-MB-231 CGP60474
3.33
uM
LJP5
 72
hr
 1235 448 4660 0.0962 -0.4119