LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 CGP60474
3.33
uM
LJP5
 72
hr
 1209 642 4203 0.1534 -0.2971
MCF7 HG-6-64-01
3.33
uM
LJP6
 72
hr
 1209 3307 4012 0.8205 0.7759
MCF7 Sorafenib
3.33
uM
LJP6
 72
hr
 1209 3843 4012 0.9590 0.9528
MCF7 Crizotinib
3.33
uM
LJP5
 72
hr
 1209 1299 4203 0.3095 0.0403
MCF7 WYE-125132
3.33
uM
LJP6
 72
hr
 1209 1170 4012 0.2922 -0.0187
MCF7 Imatinib
3.33
uM
LJP6
 72
hr
 1209 3840 4012 0.9565 0.9487
MCF7 BMS345541
3.33
uM
LJP6
 72
hr
 1209 1427 4012 0.3561 0.1001
MCF7 AZD7762
3.33
uM
LJP6
 72
hr
 1209 993 4012 0.2477 -0.1080
MCF7 CP466722
3.33
uM
LJP5
 72
hr
 1209 3332 4203 0.7963 0.7620
MCF7 GW843682X
3.33
uM
LJP6
 72
hr
 1209 1310 4012 0.3271 0.0475
MCF7 WH-4-025
3.33
uM
LJP5
 72
hr
 1209 2001 4203 0.4780 0.3251
MCF7 Neratinib
3.33
uM
LJP5
 72
hr
 1209 1390 4203 0.3315 0.0809
MCF7 Tozasertib
3.33
uM
LJP5
 72
hr
 1209 1426 4203 0.3400 0.0963
MCF7 Seliciclib
3.33
uM
LJP5
 72
hr
 1209 3016 4203 0.7184 0.6637
MCF7 CP724714
3.33
uM
LJP5
 72
hr
 1209 3762 4203 0.8966 0.8829
MCF7 SB590885
3.33
uM
LJP5
 72
hr
 1209 4070 4203 0.9685 0.9647
MCF7 Pictilisib
3.33
uM
LJP6
 72
hr
 1209 1112 4012 0.2780 -0.0470
MCF7 AT-7519
3.33
uM
LJP6
 72
hr
 1209 502 4012 0.1251 -0.3993
MCF7 HG-5-88-01
3.33
uM
LJP6
 72
hr
 1209 1982 4012 0.4938 0.3291
MCF7 AZD8055
3.33
uM
LJP6
 72
hr
 1209 985 4012 0.2457 -0.1122
MCF7 Alvocidib
3.33
uM
LJP6
 72
hr
 1209 694 4012 0.1731 -0.2752
MCF7 CGP60474
3.33
uM
LJP6
 72
hr
 1209 707 4012 0.1766 -0.2676
MCF7 Dasatinib
3.33
uM
LJP6
 72
hr
 1209 1545 4012 0.3848 0.1507
MCF7 PF562271
3.33
uM
LJP6
 72
hr
 1209 1125 4012 0.2812 -0.0405
MCF7 Palbociclib
3.33
uM
LJP6
 72
hr
 1209 1850 4012 0.4622 0.2794