LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Enzastaurin | 3.33 | uM | LJP5 | 72 | hr | 962 | 11572 | 10512 | 1.1008 | 1.0564 |
| MCF 10A | CHIR-99021 | 0.37 | uM | LJP6 | 72 | hr | 962 | 11501 | 10692 | 1.0758 | 1.0424 |
| MCF 10A | CHIR-99021 | 0.04 | uM | LJP6 | 72 | hr | 962 | 11451 | 10692 | 1.0711 | 1.0399 |
| MCF 10A | Linifanib | 1.11 | uM | LJP6 | 72 | hr | 962 | 11416 | 10692 | 1.0678 | 1.0381 |
| MCF 10A | Linifanib | 0.04 | uM | LJP6 | 72 | hr | 962 | 11413 | 10692 | 1.0675 | 1.0380 |
| MCF 10A | Celastrol | 0.04 | uM | LJP6 | 72 | hr | 962 | 11411 | 10692 | 1.0673 | 1.0378 |
| MCF 10A | Linifanib | 0.37 | uM | LJP6 | 72 | hr | 962 | 11407 | 10692 | 1.0669 | 1.0376 |
| MCF 10A | Linifanib | 0.12 | uM | LJP6 | 72 | hr | 962 | 11286 | 10692 | 1.0556 | 1.0314 |
| MCF 10A | Enzastaurin | 1.11 | uM | LJP5 | 72 | hr | 962 | 11253 | 10512 | 1.0703 | 1.0397 |
| MCF 10A | CHIR-99021 | 0.12 | uM | LJP6 | 72 | hr | 962 | 11249 | 10692 | 1.0522 | 1.0294 |
| MCF 10A | Linifanib | 3.33 | uM | LJP6 | 72 | hr | 962 | 11160 | 10692 | 1.0438 | 1.0248 |
| MCF 10A | Enzastaurin | 10 | uM | LJP5 | 72 | hr | 962 | 11123 | 10512 | 1.0580 | 1.0328 |
| MCF 10A | PD173074 | 0.04 | uM | LJP6 | 72 | hr | 962 | 11072 | 10692 | 1.0356 | 1.0202 |
| MCF 10A | Celastrol | 0.12 | uM | LJP6 | 72 | hr | 962 | 11071 | 10692 | 1.0355 | 1.0202 |
| MCF 10A | QL-X-138 | 0.04 | uM | LJP6 | 72 | hr | 962 | 11069 | 10692 | 1.0353 | 1.0201 |
| MCF 10A | CHIR-99021 | 1.11 | uM | LJP6 | 72 | hr | 962 | 11066 | 10692 | 1.0351 | 1.0198 |
| MCF 10A | TWS119 | 1.11 | uM | LJP5 | 72 | hr | 962 | 11066 | 10512 | 1.0527 | 1.0300 |
| MCF 10A | Withaferin A | 0.12 | uM | LJP5 | 72 | hr | 962 | 11032 | 10512 | 1.0495 | 1.0282 |
| MCF 10A | Nintedanib | 0.04 | uM | LJP6 | 72 | hr | 962 | 10963 | 10692 | 1.0254 | 1.0145 |
| MCF 10A | XMD11-85h | 0.04 | uM | LJP6 | 72 | hr | 962 | 10945 | 10692 | 1.0238 | 1.0134 |
| MCF 10A | XMD11-85h | 0.12 | uM | LJP6 | 72 | hr | 962 | 10944 | 10692 | 1.0236 | 1.0135 |
| MCF 10A | JW-7-24-1 | 0.04 | uM | LJP6 | 72 | hr | 962 | 10930 | 10692 | 1.0224 | 1.0127 |
| MCF 10A | A443654 | 0.04 | uM | LJP6 | 72 | hr | 962 | 10928 | 10692 | 1.0221 | 1.0126 |
| MCF 10A | GSK1059615 | 0.04 | uM | LJP5 | 72 | hr | 962 | 10852 | 10512 | 1.0323 | 1.0185 |
| MCF 10A | Enzastaurin | 0.37 | uM | LJP5 | 72 | hr | 962 | 10851 | 10512 | 1.0323 | 1.0184 |