LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T PHA-665752
10
uM
LJP5
 72
hr
 658 53 3933 0.0136 -0.6240
MDA-MB-231 Mitoxantrone
3.33
uM
LJP6
 72
hr
 1235 205 4405 0.0467 -0.6246
MDA-MB-231 Mitoxantrone
3.33
uM
LJP5
 72
hr
 1235 185 4660 0.0399 -0.6288
BT-20 Mitoxantrone
10
uM
LJP5
 72
hr
 1097 158 3846 0.0411 -0.6586
MCF7 HG-6-64-01
10
uM
LJP6
 72
hr
 1209 170 4012 0.0422 -0.6806
MDA-MB-231 PHA-665752
10
uM
LJP5
 72
hr
 1235 131 4660 0.0282 -0.6902
Hs 578T Mitoxantrone
10
uM
LJP6
 72
hr
 658 35 3761 0.0093 -0.6912
BT-20 AZD8055
10
uM
LJP6
 72
hr
 1097 119 3673 0.0326 -0.7198
Hs 578T Mitoxantrone
10
uM
LJP5
 72
hr
 658 25 3933 0.0064 -0.7202
MDA-MB-231 Mitoxantrone
10
uM
LJP6
 72
hr
 1235 108 4405 0.0247 -0.7348
MDA-MB-231 Mitoxantrone
10
uM
LJP5
 72
hr
 1235 86 4660 0.0186 -0.7515
MCF7 Mitoxantrone
10
uM
LJP5
 72
hr
 1209 89 4203 0.0213 -0.7655
SK-BR-3 Mitoxantrone
10
uM
LJP6
 72
hr
 1401 109 4168 0.0261 -0.8036
MCF7 Mitoxantrone
10
uM
LJP6
 72
hr
 1209 70 4012 0.0175 -0.8076
SK-BR-3 Mitoxantrone
10
uM
LJP5
 72
hr
 1401 91 4245 0.0217 -0.8201